ArticleJournal of biomedical optics2019
Impact of hemoglobin breakdown products in the spectral analysis of burn wounds using spatial frequency domain spectroscopy.
Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- Flap Monitoring Techniques: A Review.Journal of clinical medicine · 2024Review
- Coagulation depth estimation using a line scanner for depth-resolved laser speckle contrast imaging.Biomedical optics express · 2024Article
- Article
- Quantitative measurement of optical properties and Hb concentration in a rodent model of inflammatory Meibomian gland dysfunction using spatial frequency domain imaging.Biomedical optics express · 2022Article
- Multimodal hyperspectral fluorescence and spatial frequency domain imaging for tissue health diagnostics of the oral cavity.Biomedical optics express · 2021Article
- In Vivo Transcutaneous Monitoring of Hemoglobin Derivatives Using a Red-Green-Blue Camera-Based Spectral Imaging Technique.International journal of molecular sciences · 2021Article
- Transcutaneous monitoring of hemoglobin derivatives during methemoglobinemia in rats using spectral diffuse reflectance.Journal of biomedical optics · 2021Article
- Characterizing reduced scattering coefficient of normal human skin across different anatomic locations and Fitzpatrick skin types using spatial frequency domain imaging.Journal of biomedical optics · 2021Article
- Dual-DMD hyperspectral spatial frequency domain imaging (SFDI) using dispersed broadband illumination with a demonstration of blood stain spectral monitoring.Biomedical optics express · 2021Article
- A paintable phosphorescent bandage for postoperative tissue oxygen assessment in DIEP flap reconstruction.Science advances · 2020Article
- Handheld multispectral imager for quantitative skin assessment in low-resource settings.Journal of biomedical optics · 2020Article
- Hyperspectral imaging in the spatial frequency domain with a supercontinuum source.Journal of biomedical optics · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Burn wounds and wound healing invoke several biological processes that may complicate the interpretation of spectral imaging data. Through analysis of spatial frequency domain spectroscopy data (450 to 1000 nm) obtained from longitudinal investigations using a graded porcine burn wound healing model, we have identified features in the absorption spectrum that appear to suggest the presence of hemoglobin breakdown products, e.g., methemoglobin. Our results show that the calculated concentrations of methemoglobin directly correlate with burn severity, 24 h after the injury. In addition, tissue parameters such as oxygenation (StO2) and water fraction may be underestimated by 20% and 78%, respectively, if methemoglobin is not included in the spectral analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.