ArticleJournal of magnetic resonance imaging : JMRI2019
Paraspinal Muscle DTI Metrics Predict Muscle Strength.
Article in Journal of magnetic resonance imaging : JMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Multiparameter MRI assessment of metformin and exercise effects on skeletal muscle in prediabetes: a randomized controlled trial.European radiology experimental · 2025Trial
- Research progress of diffusion tensor imaging in lumbar degenerative diseases: a narrative review.Journal of orthopaedic surgery and research · 2026Review
- Effect of paraspinal muscle morphometry in degenerative and isthmic spondylolisthesis: an MRI study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Quantitative evaluation of cervical muscles in patients with degenerative cervical myelopathy using diffusion tensor imaging metrics.Bone & joint research · 2026Article
- Muscle Imaging Assessments in Sarcopenia: A Statement from China National Center for Orthopedics (NCO) and the East Meets West Action Group of the European Calcified Tissue Society (ECTS).Calcified tissue international · 2025Review
- Relationships between diffusion tensor parameters and measures of skeletal muscle fiber size and strength after anterior cruciate ligament injury.Magnetic resonance imaging · 2025Article
- Magnetic resonance imaging derived biomarkers for the diagnosis of type 2 diabetes with insulin resistance: A pilot study.World journal of diabetes · 2025Article
- Improved Strength Prediction Combining MRI Biomarkers of Muscle Quantity and Quality.NMR in biomedicine · 2025Article
- Assessment of muscle fiber types transformation in rats with discogenic low back pain using diffusion tensor image of paraspinal muscles.BMC medical imaging · 2025Article
- Simultaneous multi-slice technique for reducing acquisition times in diffusion tensor imaging of the knee: a feasibility study.Skeletal radiology · 2025Article
- From Voxels to Physiology: A Review of Diffusion Magnetic Resonance Imaging Applications in Skeletal Muscle.Journal of magnetic resonance imaging : JMRI · 2025Review
- Lumbar paraspinal muscles in patients with chronic non-specific low back pain and the effect of exercise: comparative and interventional study.Frontiers in rehabilitation sciences · 2025Article
- Compositional and Functional MRI of Skeletal Muscle: A Review.Journal of magnetic resonance imaging : JMRI · 2024Review
- Relationships between quantitative magnetic resonance imaging measures at the time of return to sport and clinical outcomes following acute hamstring strain injury.Journal of biomechanics · 2024Article
- Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia.BMC musculoskeletal disorders · 2024Article
- Role of End Plate Changes and Paraspinal Muscle Pathology in Lower Back Pain: A Narrative Review.Cureus · 2024Review
- Quantitative multi-parameter assessment of age- and gender-related variation of back extensor muscles in healthy adults using Dixon MR imaging.European radiology · 2024Article
- Changes in lumbar muscle diffusion tensor indices with age.BJR open · 2024Article
- Review
- Association of vastus lateralis diffusion properties with in vivo quadriceps contractile function in premenopausal women.Scandinavian journal of medicine & science in sports · 2023Article
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Authors and funding
16 authors.
Funding
Abstract
backgroundThe paraspinal muscles play an important role in the onset and progression of lower back pain. It would be of clinical interest to identify imaging biomarkers of the paraspinal musculature that are related to muscle function and strength. Diffusion tensor imaging (DTI) enables the microstructural examination of muscle tissue and its pathological changes. PURPOSE: To investigate associations of DTI parameters of the lumbar paraspinal muscles with isometric strength measurements in healthy volunteers. STUDY TYPE: Prospective. SUBJECTS: Twenty-one healthy subjects (12 male, 9 female; age = 30.1 ± 5.6 years; body mass index [BMI] = 27.5 ± 2.6 kg/m FIELD STRENGTH/SEQUENCE: 3 T/single-shot echo planar imaging (ss-EPI) DTI in 24 directions; six-echo 3D spoiled gradient echo sequence for chemical shift encoding-based water-fat separation. ASSESSMENT: Paraspinal muscles at the lumbar spine were examined. Erector spinae muscles were segmented bilaterally; cross-sectional area (CSA), proton density fat fraction (PDFF), and DTI parameters were calculated. Muscle flexion and extension maximum isometric torque values [Nm] at the back were measured with an isokinetic dynamometer and the ratio of extension to flexion strength (E/F) calculated. STATISTICAL TESTS: Pearson correlation coefficients; multivariate regression models.
resultsSignificant positive correlations were found between the ratio of extension to flexion (E/F) strength and mean diffusivity (MD) (P = 0.019), RD (P = 0.02) and the eigenvalues (λ1: P = 0.026, λ2: P = 0.033, λ3: P = 0.014). In multivariate regression models λ3 of the erector spinae muscle λ3 and gender remained statistically significant predictors of E/F (R DATA
conclusionDTI allowed the identification of muscle microstructure differences related to back muscle function that were not reflected by CSA and PDFF. DTI may potentially track subtle changes of back muscle tissue composition. LEVEL OF EVIDENCE: 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:816-823.
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