Evidence map›Paper›PMID 30723860›Full record

ArticleSaudi medical journal2019

Assessment of vancomycin utilization among Lebanese hospitals.

Diana N Malaeb, Iqbal M Fahs, Pascale Salameh, Souheil Hallit, Manal Saad, Jassem Bourji, Rabih Hallit

Open access · diamondAbstract readMulticenter Study
In one paragraph

Article in Saudi medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Diana N MalaebDepartment of Clinical Practice, Lebanese International University, Mouseitbah, Lebanon. E-mail. diana.malaeb@liu.edu.lb.
Iqbal M Fahs
Pascale Salameh
Souheil Hallit
Manal Saad
Jassem Bourji
Rabih Hallit
Lebanese University · LBLebanese International University · LBHoly Spirit University of Kaslik · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the appropriateness of vancomycin dosing and monitoring at Lebanese hospitals.

methodsThis was a multicenter retrospective study conducted at 3 Lebanese hospitals between January and March 2018. Patients 18 years of age and older treated with vancomycin for a systemic infection or prophylaxis were eligible for study enrollment. Consistency with the Infectious Diseases Society of America guidelines was evaluated to determine whether the dose of vancomycin was appropriate, as well as for the time of trough measurement, and the target concentration obtained.

resultsFrom a total of 120 patients who met the inclusion criteria, only 11 (12%) were given the appropriate maintenance dose of vancomycin with respect to actual body weight. The trough levels were monitored for 67 (55.8%) patients, with 20 (29.9%) of these patients achieving appropriate therapeutic trough levels of 15-20 mg/l. The trough concentration time measurement before the fourth dose was only carried out in 28 (41.8%) of the 67 patients.

conclusionThis study reveals a gap between the appropriate utilization of vancomycin with respect to the international guidelines in the studied Lebanese hospitals. It highlights the need for dosing and monitoring protocols suitable for vancomycin utilization in these hospitals.

Indexed as

AdolescentAdultAnti-Bacterial AgentsBody WeightCreatinineDrug MonitoringDrug Utilization ReviewFemaleGuideline AdherenceHospitalsHumansLebanonMaleMiddle AgedPractice Guidelines as TopicRetrospective StudiesAnti-Bacterial AgentsCreatinineVancomycin

Identifiers

PMID30723860
PMCPMC6402470
OpenAlexW2913104685

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.