ReviewFrontiers in veterinary science2018
Adaptation of Human Influenza Viruses to Swine.
Review in Frontiers in veterinary science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- Transmission Pathways of Zoonotic Influenza Viruses and Influencing Factors: A Systematic Review of Recent Findings.Viruses · 2025Pooled it
- Human-Origin Influenza A(H3N2) Viruses Revealed in Swine Farms During the Period 2022-2025 in Kazakhstan.Animals : an open access journal from MDPI · 2026Article
- A Retrospective Cross-Sectional Study (2009-2023): Exploring Influenza A(H1N1)pdm09 Antibody Time Series in Humans and Swine and Vaccine Coverage in Two Target Groups.Zoonoses and public health · 2026Article
- Longitudinal Surveillance of Influenza A Virus Exposure in Wild Boars (Sus scrofa) in Spain (2015-2023): Serologic and Virologic Evidence of Subtype Infections and H5N1 Spillover Risk.Zoonoses and public health · 2026Article
- Impact of maternal antibodies and weaning stress on the replication and transmission of human H3N2 influenza A in piglets.Journal of virology · 2026Article
- Management and Biosecurity Practices of Pig Farms in Nepal.Veterinary medicine and science · 2026Article
- Are Visitor and Personnel Downtime Restrictions an Effective Biosecurity Measure to Prevent the Indirect Transmission of Pathogens to Livestock?Animals : an open access journal from MDPI · 2026Review
- Vaccine-induced antigenic drift of a human-origin H3N2 Influenza A virus in swine alters glycan binding and sialic acid avidity.bioRxiv : the preprint server for biology · 2025Article
- High serological barriers may contribute to restricted Influenza-A-virus transmission between pigs and humans.One health (Amsterdam, Netherlands) · 2025Article
- Molecular and ecological determinants of mammalian adaptability in avian influenza virus.Infection · 2025Review
- Active surveillance for influenza A virus in swine reveals within-farm reassortment and cocirculation of distinct subtypes and genetic clades.Veterinary microbiology · 2025Article
- Circulation and Spillover of pdmH1N1 Influenza A Virus at an Educational Swine Farm in Chile, 2019-2023.Viruses · 2025Article
- Isolation and Characterization of H1 Subtype Swine Influenza Viruses Recently Circulating in China.Viruses · 2025Article
- Indirect contacts between Danish pig farms - what are the frequencies and risk-reducing measures, and how can they be used in simulation models?Acta veterinaria Scandinavica · 2025Article
- Passage of human-origin influenza A virus in swine tracheal epithelial cells selects for adaptive mutations in the hemagglutinin gene.PloS one · 2025Article
- Macroepidemiological trends of Influenza A virus detection through reverse transcription real-time polymerase chain reaction (RT-rtPCR) in porcine samples in the United States over the last 20 years.Frontiers in veterinary science · 2025Article
- Functional Involvement of Signal Transducers and Activators of Transcription in the Pathogenesis of Influenza A Virus.International journal of molecular sciences · 2024Review
- 2018-2019 human seasonal H3N2 influenza A virus spillovers into swine with demonstrated virus transmission in pigs were not sustained in the pig population.Journal of virology · 2024Article
- Article
- Genomic diversity and evolutionary dynamics of Influenza A viruses in Colombian swine: implications for one health surveillance and control.Emerging microbes & infections · 2024Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
A large diversity of influenza A viruses (IAV) within the H1N1/N2 and H3N2 subtypes circulates in pigs globally, with different lineages predominating in specific regions of the globe. A common characteristic of the ecology of IAV in swine in different regions is the periodic spillover of human seasonal viruses. Such human viruses resulted in sustained transmission in swine in several countries, leading to the establishment of novel IAV lineages in the swine host and contributing to the genetic and antigenic diversity of influenza observed in pigs. In this review we discuss the frequent occurrence of reverse-zoonosis of IAV from humans to pigs that have contributed to the global viral diversity in swine in a continuous manner, describe host-range factors that may be related to the adaptation of these human-origin viruses to pigs, and how these events could affect the swine industry.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.