Evidence map›Paper›PMID 30723536›Full record

ArticleOxidative medicine and cellular longevity2019

Isoflurane Preconditioning Attenuates Brain Injury Induced by Electromagnetic Pulse via the TLR4/NF

Jiang-Jing Li, Bin Deng, Xia-Jing Zhang, Miao-Miao Lv, Hui Zhao, Jin Wang, Ji-Dong Liu, Rui-Li Han, Xu-De Sun

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiang-Jing LiDepartment of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.ORCID 0000-0003-0314-9815
Bin DengDepartment of Anesthesiology, Xiang'an Hospital of Xiamen University, Xiamen 361101, China.
Xia-Jing ZhangDepartment of Anesthesiology, Fourth Hospital of Xi'an, Xi'an 710038, China.ORCID 0000-0001-5620-7076
Miao-Miao LvDepartment of Anesthesiology, The 323 Hospital of PLA, Xi'an 710054, China.ORCID 0000-0003-2751-0003
Hui ZhaoDepartment of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.ORCID 0000-0002-6725-8888
Jin WangDepartment of Preventive Medicine, Air Force Medical University, Xi'an 710038, China.ORCID 0000-0001-7059-8317
Ji-Dong LiuOutpatient Department, Ministry of Foreign Affairs of the People's Republic of China, Beijing 100701, China.ORCID 0000-0001-8061-0412
Rui-Li HanDepartment of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.ORCID 0000-0001-6450-6770
Xu-De SunDepartment of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.ORCID 0000-0002-2348-6723
Air Force Medical University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electromagnetic pulse (EMP) is a unique type of electromagnetic radiation, and EMP exposure causes a series of biological effects. The nervous system is sensitive to EMP. We studied the neuroprotective effects of isoflurane preconditioning against EMP exposure and used hematoxylin-eosin staining (HE) to observe the effects of electromagnetic pulse and isoflurane preconditioning on neurons. Inflammatory cytokines were detected by enzyme-linked immunosorbent assay (ELISA). Western blotting was used to detect the expression of caspase-3, CD11b, TLR4, and NF

Indexed as

Electromagnetic PhenomenaAnimalsBrain InjuriesHumansIsofluraneMaleNF-kappa BRatsRats, Sprague-DawleySignal TransductionToll-Like Receptor 4IsofluraneNF-kappa BToll-Like Receptor 4

Identifiers

PMID30723536
PMCPMC6339739
OpenAlexW2907732731

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.