ArticleScientific reports2019
Novel anti-biofouling light-curable fluoride varnish containing 2-methacryloyloxyethyl phosphorylcholine to prevent enamel demineralization.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Influence of Machining, Polishing, and Glazing on Surface Properties and Biological Performance of Zirconia and Lithium Disilicate Dental Ceramics.Journal of functional biomaterials · 2025Article
- Antibacterial activity and physicochemical properties of light-curable fluoride varnishes containing strontium phosphate-based glass.Clinical oral investigations · 2025Article
- Enhanced anti-microbial properties of clear aligner resin containing zwitterionic material.Scientific reports · 2025Article
- Zinc-modified phosphate-based glass micro-filler improves Candida albicans resistance of auto-polymerized acrylic resin without altering mechanical performance.Scientific reports · 2022Article
- A novel methacrylate derivative polymer that resists bacterial cell-mediated biodegradation.Journal of biomedical materials research. Part B, Applied biomaterials · 2022Article
- Efficacy of CPP-ACP fluoride varnish applied with and without acid etching in preventing enamel demineralization compared to light-curable fluoride varnish.The Angle orthodontist · 2022Article
- Bio-inspired special wettability in oral antibacterial applications.Frontiers in bioengineering and biotechnology · 2022Review
- Recent Advances in the Development of Antimicrobial and Antifouling Biocompatible Materials for Dental Applications.Materials (Basel, Switzerland) · 2021Review
- Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material ContainingMolecules (Basel, Switzerland) · 2021Article
- Durable Oral Biofilm Resistance of 3D-Printed Dental Base Polymers Containing Zwitterionic Materials.International journal of molecular sciences · 2021Article
- Bio-Interactive Zwitterionic Dental Biomaterials for Improving Biofilm Resistance: Characteristics and Applications.International journal of molecular sciences · 2020Review
- Development of a Bioactive Flowable Resin Composite Containing a Zinc-Doped Phosphate-Based Glass.Nanomaterials (Basel, Switzerland) · 2020Article
- Application of Antimicrobial Polymers in the Development of Dental Resin Composite.Molecules (Basel, Switzerland) · 2020Review
- Resin-Based Sealant with Bioactive Glass and Zwitterionic Material for Remineralisation and Multi-Species Biofilm Inhibition.Nanomaterials (Basel, Switzerland) · 2020Article
- Analysis of the Antimicrobial, Cytotoxic, and Antioxidant Activities ofPlants (Basel, Switzerland) · 2020Article
- Use of Protein Repellents to Enhance the Antimicrobial Functionality of Quaternary Ammonium Containing Dental Materials.Journal of functional biomaterials · 2020Review
- Incorporation of zwitterionic materials into light-curable fluoride varnish for biofilm inhibition and caries prevention.Scientific reports · 2019Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluated the efficacy of light-curable fluoride varnish (LCFV) that contains 2-methacryloyloxyethyl phosphorylcholine (MPC) in terms of anti-biofouling properties and prevention of tooth enamel demineralization. MPC was mixed with and incorporated into LCFV at 0 (control), 1.5, 3.0, 5.0, 10.0, 20.0, and 40.0 weight percentage (wt%). Addition of high wt% of MPC resulted in increased film thickness and decreased the degree of conversion, indicating loss of the advantageous properties of LCFV. Addition of 1.5, 3, or 5 wt% MPC significantly reduced the amount of bovine serum albumin adsorbed from a solution and proteins adsorbed from brain heart infusion medium compared to the control (P < 0.001). A similar pattern was observed for bacterial adhesion: significantly less Streptococcus mutans cells adhered on the surface of LCFV with 1.5, 3, or 5 wt% MPC (P < 0.001) than on the control, and similar results were obtained for Actinomyces naeslundii and Streptococcus sanguinis adherence to LCFV with 3 wt% MPC. Finally, bacterial adhesion, surface microhardness loss, and the depth of demineralization were substantially lower on bovine tooth enamel surface coated with LCFV containing 3 wt% of MPC than in the control treatment (0 wt% MPC). Therefore, this novel LCFV containing a low concentration of MPC (e.g., 3 wt%) would be effective in anti-biofouling while maintaining the important advantageous features of light-curable fluoride in preventing demineralization.
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