Evidence map›Paper›PMID 30723176›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2019

A Prospective Targeted Serum Metabolomics Study of Pancreatic Cancer in Postmenopausal Women.

Li Jiao, Suman Maity, Cristian Coarfa, Kimal Rajapakshe, Liang Chen, Feng Jin, Vasanta Putluri, Lesley F Tinker, Qianxing Mo, Fengju Chen and 4 more

Abstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Li JiaoSection of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas. jiao@bcm.edu.
Suman MaityDan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas.
Cristian CoarfaAdvanced Technology Core, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-4183-4939
Kimal RajapaksheTexas Medical Center Digestive Disease Center, Houston, Texas.
Liang ChenSection of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas.
Feng JinDan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas.
Vasanta PutluriDan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas.
Lesley F TinkerCenter for Translational Research on Inflammatory Diseases (CTRID), Michael E. DeBakey VA Medical Center, Houston, Texas.
Qianxing MoDan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas.
Fengju ChenAdvanced Technology Core, Baylor College of Medicine, Houston, Texas.
Subrata SenDepartment of Translational Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.
Haleh Sangi-HyghpeykarDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.
Hashem B El-SeragSection of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas.ORCID 0000-0001-5964-7579
Nagireddy PutluriAdvanced Technology Core, Baylor College of Medicine, Houston, Texas.

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Women's Health Initiative Clinical Coordinating CenterN01WH22110 · WH · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PRENTICE, ROSS L · 2007 to 2010
$22.5M
Women's Health Initiative Memory Study (WHIMS)N01WH44221 · WH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2009 to 2010
$3.1M
Racial Disparity in Bladder Cancer and Identification of Altered Metabolism in African American Compare to European Bladder CancerR01CA220297 · NCI · BAYLOR COLLEGE OF MEDICINE · PI PUTLURI, NAGIREDDY · 2017 to 2021
$1.8M
Advanced Glycation End-Products and Risk of Pancreatic CancerR01CA172880 · NCI · BAYLOR COLLEGE OF MEDICINE · PI JIAO, LI · 2013 to 2015
$1.6M
VANGUARD CENTER FOR WOMEN'S HEALTH INITIATIVEN01WH032111 · WH · EMORY UNIVERSITY · PI WATTS, NELSON · 1993 to 2001
$1.6M
WOMENS HEALTH INITIATIVE-N01WH22110N01WH022110 · WH · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ROSS, PRENTICE · 1992 to 2006
$1.2M
VANGUARD CENTER FOR WOMEN'S HEALTH INITIATIVEN01WH032119 · WH · MEMORIAL HOSPITAL OF RHODE ISLAND · PI ASSAF, ANNLOUISE R. · 1993 to 2000
$1.2M
VANGUARD CENTER FOR WOMENS HEALTH INITIATIVEN01WH032100 · WH · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BERESFORD, SHIRLEY AA · 1993 to 2001
$1.1M
VANGUARD CENTER FOR WOMENS HEALTH INITIATIVEN01WH032108 · WH · NORTHWESTERN UNIVERSITY · PI GREENLAND, PHILIP · 1993 to 2000
$919k
CLIN CTR CLIN TRIAL/OBSERVATIONAL STUDY OF WHIN01WH042129 · WH · UNIVERSITY OF FLORIDA · PI LIMACHER, MARIAN C. · 1994 to 2000
$868k
Women's Health Initiative Field CenterN01WH24152 · WH · UNIV OF MED/DENT OF NJ-SCHOOL OF NURSING · PI LASSER, NORMAN · 2007 to 2009
$648k
HSRD VA I50 HX001236NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA172880NCI NIH HHS R01 CA220297NHLBI NIH HHS HHSN268201100046CNHLBI NIH HHS HHSN268201600018CNHLBI NIH HHS N01WH32105NHLBI NIH HHS N01WH32118NHLBI NIH HHS N01WH42107WHI NIH HHS N01WH22110WHI NIH HHS N01WH24152WHI NIH HHS N01WH32100WHI NIH HHS N01WH32108WHI NIH HHS N01WH32111WHI NIH HHS N01WH32115WHI NIH HHS N01WH32119WHI NIH HHS N01WH42129WHI NIH HHS N01WH44221
6 · The paper itself

Abstract

To examine the association between metabolic deregulation and pancreatic cancer, we conducted a two-stage case-control targeted metabolomics study using prediagnostic sera collected one year before diagnosis in the Women's Health Initiative study. We used the LC/MS to quantitate 470 metabolites in 30 matched case/control pairs. From 180 detectable metabolites, we selected 14 metabolites to be validated in additional 18 matched case/control pairs. We used the paired

Indexed as

MetabolomeAgedBiomarkers, TumorCase-Control StudiesFemaleHumansMetabolomicsMiddle AgedPancreatic NeoplasmsPostmenopauseProspective StudiesBiomarkers, Tumor

Identifiers

PMID30723176
PMCPMC6445762

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.