Evidence map›Paper›PMID 30723148›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Engineered resistance to Zika virus in transgenic

Anna Buchman, Stephanie Gamez, Ming Li, Igor Antoshechkin, Hsing-Han Li, Hsin-Wei Wang, Chun-Hong Chen, Melissa J Klein, Jean-Bernard Duchemin, Prasad N Paradkar and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 105 citations in OpenAlex.

  1. Review
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  5. ExploitingPathogens (Basel, Switzerland) · 2025
    Review
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  15. CLEC5A mediates Zika virus-induced testicular damage.Journal of biomedical science · 2023
    Article
  16. Engineered Antiviral Sensor Targets Infected Mosquitoes.bioRxiv : the preprint server for biology · 2023
    Article
  17. Article
  18. Article
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  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Anna BuchmanSection of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093.
Stephanie GamezSection of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093.
Ming LiSection of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093.
Igor AntoshechkinDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Hsing-Han LiInstitution of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan 30013.
Hsin-Wei WangNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, Taiwan.
Chun-Hong ChenNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, Taiwan.
Melissa J KleinCSIRO Health and Biosecurity, Australian Animal Health Laboratory, Geelong, VIC 3220, Australia.
Jean-Bernard DucheminCSIRO Health and Biosecurity, Australian Animal Health Laboratory, Geelong, VIC 3220, Australia.ORCID 0000-0001-5044-4855
Prasad N ParadkarCSIRO Health and Biosecurity, Australian Animal Health Laboratory, Geelong, VIC 3220, Australia; prasad.paradkar@csiro.au oakbari@ucsd.edu.
Omar S AkbariSection of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093; prasad.paradkar@csiro.au oakbari@ucsd.edu.ORCID 0000-0002-6853-9884
University of California San Diego · USAustralian Centre for Disease Preparedness · AUNational Health Research Institutes · TWCalifornia Institute of Technology · US

Funding

Developing reciprocal chromosomal translocations for wild population replacement in an important vector of human disease.R21AI123937 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AKBARI, OMAR SULTAN · 2017 to 2018
$427k
Synthetically engineering population control systems in vectors of human diseaseK22AI113060 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AKBARI, OMAR SULTAN · 2015 to 2016
$270k
NIAID NIH HHS K22 AI113060NIAID NIH HHS R21 AI123937
6 · The paper itself

Abstract

Recent Zika virus (ZIKV) outbreaks have highlighted the necessity for development of novel vector control strategies to combat arboviral transmission, including genetic versions of the sterile insect technique, artificial infection with

Indexed as

AnimalsAnimals, Genetically ModifiedDisease OutbreaksHumansMosquito VectorsSalivaViral LoadWolbachiaZika VirusZika Virus InfectionAedesaegyptimosquitoresistanceZIKA

Identifiers

PMID30723148
PMCPMC6397566
OpenAlexW2805503715

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.