Evidence map›Paper›PMID 30723124›Full record

ArticlemBio2019

The Small RNA Teg41 Regulates Expression of the Alpha Phenol-Soluble Modulins and Is Required for Virulence in Staphylococcus aureus.

Rachel L Zapf, Richard E Wiemels, Rebecca A Keogh, Donald L Holzschu, Kayla M Howell, Emily Trzeciak, Andrew R Caillet, Kellie A King, Samantha A Selhorst, Michael J Naldrett and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 42 citations in OpenAlex.

  1. Discovery ofmBio · 2026
    Article
  2. Article
  3. Article
  4. Calprotectin protectsmSystems · 2025
    Article
  5. Activation of themBio · 2025
    Article
  6. Article
  7. YjbH contributes toVirulence · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Thirty Years of sRNA-Mediated Regulation inInternational journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Rachel L Zapf *Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Richard E Wiemels *Department of Biological Sciences, Ohio University, Athens, Ohio, USA.
Rebecca A KeoghDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA.
Donald L HolzschuDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA.
Kayla M HowellDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA.
Emily TrzeciakDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA.
Andrew R CailletDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA.
Kellie A KingDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA.
Samantha A SelhorstDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA.
Michael J NaldrettProteomics and Metabolomics Facility, Center for Biotechnology, University of Nebraska Lincoln, Lincoln, Nebraska, USA.
Jeffrey L BoseDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Ronan K CarrollDepartment of Biological Sciences, Ohio University, Athens, Ohio, USA carrolr3@ohio.edu.ORCID 0000-0001-7090-3414
Ohio University · USUniversity of Kansas Medical Center · USUniversity of Nebraska–Lincoln · US

Funding

Mechanistic control of metabolism and virulence by fatty acid kinase in MRSAR01AI121073 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BOSE, JEFFREY LEE · 2016 to 2020
$1.9M
Characterizing the role of PrsB, an intracellular PPIase that is required for activity of secreted virulence factors in Staphylococcus aureusR21AI128376 · NIAID · OHIO UNIVERSITY ATHENS · PI CARROLL, RONAN · 2017 to 2018
$415k
NIAID NIH HHS R01 AI121073NIAID NIH HHS R21 AI128376
6 · The paper itself

Abstract

Small RNAs (sRNAs) remain an understudied class of regulatory molecules in bacteria in general and in Gram-positive bacteria in particular. In the major human pathogen

Indexed as

Gene Expression Regulation, BacterialAbscessAnimalsBacterial ToxinsDisease Models, AnimalGenetic Complementation TestHemolysisHumansMiceRNA, BacterialRNA, Small UntranslatedSequence DeletionStaphylococcal InfectionsStaphylococcus aureusVirulenceVirulence FactorsBacterial ToxinsRNA, BacterialRNA, Small Untranslatedstaphylococcal delta toxinVirulence Factorsphenol-soluble modulinPSMregulatory RNAsRNAStaphylococcus aureusTeg41

Identifiers

PMID30723124
PMCPMC6428751
OpenAlexW2913682882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.