Evidence map›Paper›PMID 30722795›Full record

SynthesisPsychological medicine2020

Migration and psychosis: a meta-analysis of incidence studies.

Jean-Paul Selten, Els van der Ven, Fabian Termorshuizen

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Psychological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 14 pooled it
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 14 syntheses or guidelines pooled it, 227 citations in OpenAlex.

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  8. The ethnic density effect in psychosis: a systematic review and multilevel meta-analysis.The British journal of psychiatry : the journal of mental science · 2021
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52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jean-Paul SeltenSchool for Mental Health and Neuroscience, University of Maastricht, Maastricht, The Netherlands.ORCID 0000-0003-1591-3243
Els van der VenSchool for Mental Health and Neuroscience, University of Maastricht, Maastricht, The Netherlands.ORCID 0000-0002-3432-261X
Fabian TermorshuizenGGZ Rivierduinen, Institute for Mental Health, Leiden, The Netherlands.ORCID 0000-0001-9316-7659
Maastricht University · NLGGZ Rivierduinen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aims of this meta-analysis are (i) to estimate the pooled relative risk (RR) of developing non-affective psychotic disorder (NAPD) and affective psychotic disorder (APD) among migrants and their children; (ii) to adjust these results for socioeconomic status (SES); (iii) to examine the sources of heterogeneity that underlie the risk of NAPD.

methodsWe included population-based incidence studies that reported an age-adjusted RR with 95% confidence interval (CI) published 1 January 1977-12 October 2017 and used a random-effects model.

resultsWe retrieved studies performed in Europe (n = 43), Israel (n = 3), Canada (n = 2) and Australia (n = 1). The meta-analysis yielded a RR, adjusted for age and sex, of 2.13 (95% CI 1.99-2.27) for NAPD and 2.94 (95% CI 2.28-3.79) for APD. The RRs diminished, but persisted after adjustment for SES. With reference to NAPD: a personal or parental history of migration to Europe from countries outside Europe was associated with a higher RR (RR = 2.94, 95% CI 2.63-3.29) than migration within Europe (RR = 1.88, 95% 1.62-2.18). The corresponding RR was lower in Israel (RR = 1.22; 0.99-1.50) and Canada (RR = 1.21; 0.85-1.74). The RR was highest among individuals with a black skin colour (RR = 4.19, 95% CI 3.42-5.14). The evidence of a difference in risk between first and second generation was insufficient.

conclusionsPositive selection may explain the low risk in Canada, while the change from exclusion to inclusion may do the same in Israel. Given the high risks among migrants from developing countries in Europe, social exclusion may have a pathogenic role.

Indexed as

AustraliaCanadaCohort StudiesEuropeFemaleHumansIsraelMalePsychotic DisordersSex FactorsTransients and MigrantsBipolar disorderdepressive disorderdopamineethnicitymigrationpsychosisraceschizophreniasocial exclusionstress

Identifiers

PMID30722795
PMCPMC7083571
OpenAlexW2912941833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.