ArticleThe Australian and New Zealand journal of psychiatry2019
The iHOPE-20 study: Relationships between and prospective predictors of remission, clinical recovery, personal recovery and resilience 20 years on from a first episode psychosis.
Article in The Australian and New Zealand journal of psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Personal Recovery in People With a Psychotic Disorder: A Systematic Review and Meta-Analysis of Associated Factors.Frontiers in psychiatry · 2021Pooled it
- Rate and predictors of remission and recovery in first-episode psychosis: A 12-year follow-up of randomized-controlled trial on early intervention.Molecular psychiatry · 2026Trial
- The effect of Soteria on personal recovery in early episode psychosis - a two-year naturalistic cohort comparison with care as usual.Social psychiatry and psychiatric epidemiology · 2026Article
- Long-Term Trajectories of Multidimensional Outcomes in Psychosis Following Early Intervention During the Critical Period: The PEPP-Montreal 10+ Study Protocol.Early intervention in psychiatry · 2026Article
- Social network reductions are associated with negative symptoms in schizophrenia.Social psychiatry and psychiatric epidemiology · 2025Article
- "Why shouldn't I expect a lot from life?" - a qualitative study of what facilitates long-term recovery in first-episode psychosis.BMC psychiatry · 2025Article
- Multidimensional outcome of first-episode psychosis: a network analysis.Psychological medicine · 2025Article
- Taking what you get or Getting what you Need: A Qualitative Study on Experiences with Mental Health and Welfare Services in Long-Term Recovery in First-Episode Psychosis.Community mental health journal · 2025Article
- Longitudinal recovery and self-efficacy in first-episode schizophrenia: insights from a 10-year follow-up study.Frontiers in psychiatry · 2025Article
- A 10-Year Longitudinal Study of Brain Cortical Thickness in People with First-Episode Psychosis Using Normative Models.Schizophrenia bulletin · 2024Article
- Long-term clinical recovery and treatment resistance in first-episode psychosis: a 10-year follow-up study.Schizophrenia (Heidelberg, Germany) · 2024Article
- A good life with psychosis: rate of positive outcomes in first-episode psychosis at 10-year follow-up.Psychological medicine · 2024Article
- Adult Attachment and Personal Recovery in Clients With a Psychotic Disorder.Schizophrenia bulletin open · 2023Article
- Three-year outcomes and predictors for full recovery in patients with early-stage psychosis.Schizophrenia (Heidelberg, Germany) · 2022Article
- The Time is Ripe for a Consensus Definition of Clinical Recovery in First-episode Psychosis: Suggestions Based on a 10-Year Follow-up Study.Schizophrenia bulletin · 2022Article
- Central Oxidative Stress and Early Vocational Outcomes in First Episode Psychosis: A 7-Tesla Magnetic Resonance Spectroscopy Study of Glutathione.Schizophrenia bulletin · 2022Article
- Long-Term Outcomes of First-Admission Psychosis: A Naturalistic 21-Year Follow-Up Study of Symptomatic, Functional and Personal Recovery and Their Baseline Predictors.Schizophrenia bulletin · 2022Article
- A qualitative study exploring personal recovery meaning and the potential influence of clinical recovery status on this meaning 20 years after a first-episode psychosis.Social psychiatry and psychiatric epidemiology · 2022Article
- Implementation of first episode psychosis intervention in India - A case study in a low-and middle-income country.SSM. Mental health · 2021Article
- Clinical, societal and personal recovery in schizophrenia spectrum disorders across time: states and annual transitions.The British journal of psychiatry : the journal of mental science · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveKnowledge of outcome in psychotic illness is limited by the paucity of very long-term epidemiologically representative studies of incidence first episode psychosis (FEP) cohorts that measure and compare outcomes reflecting modern clinical practice, mental health policy and research agendas. Our study aimed to address this gap.
methodiHOPE-20 is a prospective 20-year follow-up study of a FEP incidence cohort (
resultsAt follow-up, 20 out of 171 cohort members (11.70%) were deceased. We assessed 80 out of 151 alive cohort members (53% recruitment rate); 65% were in remission; 35.2% were in Full Functional Recovery and 53.7% confirmed they were fully recovered according to their personal definition of recovery. A complex array of relationships between outcomes was found. Outcomes were better for people who had a short duration of untreated psychosis, displayed higher premorbid social adjustment (between the ages of 5-11) and at baseline, were older, not living alone, in full-time employment, given a non-affective diagnosis, and had lower Global Assessment of Functioning scores.
conclusionAmong participants, full remission of psychotic symptoms and personally defined recovery was not just possible but likely in the very long term. However, attaining positive functional outcomes and building resilience in FEP remain key challenges for mental health services.
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