ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019
Interrelated Neuromuscular and Clinical Risk Factors That Contribute to Falls.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature.International journal of environmental research and public health · 2023Pooled it
- Clinical Characterization of Hip Subgroups in Geriatric Chronic Low Back Pain.Archives of physical medicine and rehabilitation · 2025Article
- Linking Neurocardiovascular Responses in the Active Stand Test to Adverse Outcomes: Insights from the Irish Longitudinal Study on Ageing (TILDA).Sensors (Basel, Switzerland) · 2025Article
- Understanding the Association of Older Adult Fall Risk Factors by Age and Sex Through Factor Analysis.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023Article
- Mild Neurocognitive Disorder, Social Engagement, and Falls Among Older Primary Care Patients.Archives of physical medicine and rehabilitation · 2023Article
- Innovations in Geroscience to enhance mobility in older adults.Experimental gerontology · 2020Review
- Peripheral Nerve Impairment and Recurrent Falls Among Women: Results From the Study of Women's Health Across the Nation.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- When Will My Patient Fall? Sensor-Based In-Home Walking Speed Identifies Future Falls in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundNeuromuscular and clinical factors contribute to falls among older adults, yet the interrelated nature of these factors is not well understood. We investigated the relationships between these factors and how they contribute to falls, which may help optimize fall risk assessment and prevention.
methodsA total of 365 primary care patients (age = 77 ± 7, 67% female) were included from the Boston Rehabilitative Impairment Study of the Elderly. Neuromuscular measures included leg strength and leg velocity, trunk extensor endurance, and knee range of motion. Clinical measures included memory, executive function, depressive symptoms, pain, sensory loss, vision, comorbidity, physical activity, mobility self-efficacy, and psychiatric medication. Factor analysis was used to evaluate clustering of factors. Negative binomial regression assessed the relationship of factors with three-year fall rate. Interactions were tested to examine whether clinical factors modified the relationship between neuromuscular factors and falls.
resultsThree factors emerged: (i) neuromuscular factors, pain, and self-efficacy; (ii) memory; and (iii) executive function. Having three neuromuscular impairments predicted higher fall rate (incidence rate ratio [95% confidence interval]: 3.39 [1.82-6.32]) but was attenuated by memory (1.69 [1.10-2.61]), mobility self-efficacy (0.99 [0.98-0.99]), psychiatric medication use (1.54 [1.10-2.14]), and pain (1.13 [1.04-1.23]). Pain modified the relationship between neuromuscular impairment burden (number of neuromuscular impairments) and falls. Having three neuromuscular impairments was associated with a higher fall rate in patients with high levels of pain (5.73 [2.46-13.34]) but not among those with low pain.
conclusionsNeuromuscular impairment burden was strongly associated with fall rate in older adults with pain. These factors should be considered together during fall risk assessment, post fall assessment, and prevention.
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