Evidence map›Paper›PMID 30721922›Full record

ArticleBioinformatics (Oxford, England)2019

G4Hunter web application: a web server for G-quadruplex prediction.

Václav Brázda, Jan Kolomazník, Jiří Lýsek, Martin Bartas, Miroslav Fojta, Jiří Šťastný, Jean-Louis Mergny

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

136 citing papers in PubMed.

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  20. Investigating Potential 5' UTR G-Quadruplexes Within NRF2 mRNA.Current issues in molecular biology · 2026
    Article

76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Václav BrázdaDepartment of biophysical chemistry and molecular oncology, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic.
Jan KolomazníkDepartment of Informatics, Mendel University in Brno, Brno, Czech Republic.
Jiří LýsekDepartment of Informatics, Mendel University in Brno, Brno, Czech Republic.
Martin BartasDepartment of biophysical chemistry and molecular oncology, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic.
Miroslav FojtaDepartment of biophysical chemistry and molecular oncology, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic.
Jiří ŠťastnýDepartment of Informatics, Mendel University in Brno, Brno, Czech Republic.
Jean-Louis MergnyDepartment of biophysical chemistry and molecular oncology, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

motivationExpanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community.

resultsWe developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete characterization of localization and quadruplex propensity of quadruplex-forming sequences. The G4Hunter web application includes an interactive graphical data representation with many useful options including visualization, sorting, data storage and export. AVAILABILITY AND IMPLEMENTATION: G4Hunter web application can be accessed at: http://bioinformatics.ibp.cz. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

G-QuadruplexesComputersDNAGuanineInternetSequence Analysis, DNASoftwareDNAGuanine

Identifiers

PMID30721922
PMCPMC6748775

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.