Evidence map›Paper›PMID 30721768›Full record

ArticleBrain research bulletin2019

Chronic insulinopenia/hyperglycemia decreases cannabinoid CB

Liane I F Moura, Cristina Lemos, Catherine Ledent, Eugénia Carvalho, Attila Köfalvi

Open access · bronzeAbstract read
In one paragraph

Article in Brain research bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Astrocytic GPR55 receptors promote glycolysis.Journal of cannabis research · 2026
    Article
  2. Article
  3. Article
  4. Transient gain of function of cannabinoid CBBrain research bulletin · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Liane I F MouraCNC, Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
Cristina LemosCNC, Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal; Experimental Psychiatry Unit, Center for Psychiatry and Psychotherapy, Medical University Innsbruck, Austria.
Catherine LedentIRIBHM, Université Libre de Bruxelles, Brussels B-1070, Belgium.
Eugénia CarvalhoCNC, Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal; Arkansas Children's Research Institute, Little Rock, Arkansas 72202, United States; The Portuguese Diabetes Association (APDP), Lisbon, Portugal; Department of Geriatrics, University of Arkansas for Medical Sciences, Arkansas 72205, United States.
Attila KöfalviCNC, Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal; Institute for Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal. Electronic address: akofalvi@uc.pt.
University of Coimbra · PTArkansas Children's Hospital · USInnsbruck Medical University · ATUniversité Libre de Bruxelles · BE

Funding

The Role of the Mitochondrion in the Metabolic Stress Response to Burn TraumaP20GM109096 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI PORTER, CRAIG · 2016 to 2025
$20.7M
RESOURCE CORE 3: ANALYTICAL COREP30AG028718 · NIA · UNIV OF ARKANSAS FOR MED SCIS · PI WEI, JEANNE Y · 2011 to 2015
$5.1M
NIA NIH HHS P30 AG028718NIGMS NIH HHS P20 GM109096
6 · The paper itself

Abstract

Both endocannabinoids and insulin regulate peripheral and cerebral glucose homeostasis via convergent signaling pathways that are impacted by diabetes. Here we asked how glucose metabolism and important facets of insulin signaling are affected in the forebrain of cannabinoid CB

Indexed as

AnimalsCannabinoidsDiabetes Mellitus, ExperimentalEndocannabinoidsGlucoseHippocampusHyperglycemiaInsulinMaleMiceMice, KnockoutProsencephalonReceptor, Cannabinoid, CB1Signal TransductionCannabinoidsEndocannabinoidsGlucoseInsulinReceptor, Cannabinoid, CB1cannabinoid CB(1)receptor knockoutdiabetesfrontal cortexglucose uptakehippocampusinsulinstreptozotocin

Identifiers

PMID30721768
PMCPMC6420377
OpenAlexW2912772031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.