ArticleJournal of applied clinical medical physics2019
Dose evaluation indices for total body irradiation using TomoDirect with different numbers of ports: A comparison with the TomoHelical method.
Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Dosimetric impact of port number in TomoDirect-based lower-body total body irradiation.Journal of applied clinical medical physics · 2026Article
- A novel AP/PA total body irradiation technique using abutting IMRT fields at extended SSD.Journal of applied clinical medical physics · 2024Article
- Considerations for intensity modulated total body or total marrow and lymphoid irradiation.Clinical and translational radiation oncology · 2023Article
- Optimised conformal total body irradiation: a heterogeneous practice, so where next?The British journal of radiology · 2023Review
- Intensity-modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles.Journal of applied clinical medical physics · 2020Article
- Feasibility of hybrid TomoHelical- and TomoDirect-based volumetric gradient matching technique for total body irradiation.Radiation oncology (London, England) · 2019Article
- Clinical implementation of low-dose total body irradiation using topotherapy technique.Physics and imaging in radiation oncology · 2019Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
TomoDirect has been reported to have some advantages over TomoHelical in delivering total body irradiation (TBI). This study aimed to investigate the relationships between the number of ports and the dose evaluation indices in low-dose TBI in TomoDirect mode using 2-12 ports and to compare these data with those for the TomoHelical mode in a simulation study. Thirteen patients underwent low-dose TBI in TomoHelical mode from June 2015 to June 2016. We used the same computed tomography data sets for these patients to create new treatment plans for upper-body parts using TomoDirect mode with 2-12 beam angles as well as TomoHelical mode. The prescription was 4 Gy in two equal fractions. For the TomoDirect data, we generated plans with 2-12 ports with approximately equally spaced angles; the modulation factor, field width, and pitch were 2.0, 5.0 cm, and 0.500, respectively. For the TomoHelical plans, the modulation factor, field width, and pitch were 2.0, 5.0 cm, and 0.397, respectively. D2, D98, D50, and the homogeneity index (HI) were evaluated to compare TomoDirect plans having 2-12 ports with the TomoHelical plan. Using TomoDirect plans, D2 with four ports or fewer, D98 with 10 ports or fewer, D50 with four ports or fewer and HI with five ports or fewer showed statistically significantly worse results than the TomoHelical plan. With the TomoDirect plans, D2 with seven ports or more, D50 with eight ports or more, and HI with eight ports or more showed statistically significant improvement compared with the TomoHelical plan. All of the dose evaluation indices of the TomoDirect plans showed a tendency to improve as the number of ports increased. TomoDirect plans showed statistically significant improvement of D2, D50, and HI compared with the TomoHelical plan. Therefore, we conclude that TomoDirect can provide better dose distribution in low-dose TBI with TomoTherapy.
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