Evidence map›Paper›PMID 30721415›Full record

ArticleLasers in medical science2019

Photobiomodulation can alter mRNA levels cell death-related.

Pierre Augusto Victor da Silva, Lúcia Mara Januário Dos Anjos, Thais Fraga Abduch, Rafael Pereira, Adenilson de Souza da Fonseca, Flávia de Paoli

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Photobiomodulation at 830 nm Stimulates Migration, Survival and Proliferation of Fibroblast Cells.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Pierre Augusto Victor da SilvaDepartamento de Fisioterapia, Centro Universitário Redentor (UniRedentor), BR 356, nº 25 - Cidade Nova, Itaperuna / Rio de Janeiro, 28300-000, Brazil. pierreaugusto@gmail.com.ORCID http://orcid.org/0000-0002-6367-9482
Lúcia Mara Januário Dos AnjosDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Rua José Lourenço Kelmer, s/n-Campus Universitário, São Pedro, Juiz de Fora, Minas Gerais, 36036-900, Brazil.
Thais Fraga AbduchDepartamento de Fisioterapia, Faculdade de Ciências Médicas e da Saúde (SUPREMA), Alameda Salvaterra, nº. 200, Bairro Salvaterra, Juiz de Fora, Minas Gerais, 36033-003, Brazil.
Rafael PereiraDepartamento de Ciências Biológicas, Universidade Estadual do Sudoeste da Bahia (UESB), Jequié, Bahia, 45210-506, Brazil.
Adenilson de Souza da FonsecaDepartamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, Vila Isabel, Rio de Janeiro, 20551-030, Brazil.
Flávia de PaoliDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Rua José Lourenço Kelmer, s/n-Campus Universitário, São Pedro, Juiz de Fora, Minas Gerais, 36036-900, Brazil.
Universidade Federal de Juiz de Fora · BRDepartamento de Ciência e Tecnologia · BRFaculdade Redentor · BRSouthwest Bahia State University · BRUniversidade do Estado do Rio de Janeiro · BR

Funding

Conselho Nacional de Pesquisa e Desenvolvimento-CNPq APQ 474405/2013-3Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais APQ 02123/15
6 · The paper itself

Abstract

Photobiomodulation (PBM) by low-level laser has demonstrated excellent results for inflammatory treatments, promoting repair of injured tissues. Knowledge regarding the molecular mechanisms involved in this process has been increasing, but its effect on cell death/survival-related gene expression after laser irradiation with different doses is not well understood. So, it is important to know these effects in order to guarantee the safety of therapeutic protocols based on PBM. This study aimed to investigate the mRNA levels of genes related to proteins involved in cell death/survival pathways of healthy tissues from talocrural joint of mice after PBM. Mice were divided into three groups: control, PBM at 3 J cm

Indexed as

Low-Level Light TherapyAnimalsApoptosisbcl-2-Associated X ProteinDNA FragmentationGene Expression RegulationMaleMice, Inbred C57BLRNA, Messengerbcl-2-Associated X ProteinRNA, MessengerApoptosisBcl-2/Bax ratioCaspaseDNA fragmentationPhotobiomodulation

Identifiers

PMID30721415
OpenAlexW2913046811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.