ArticlePLoS computational biology2019
Available energy fluxes drive a transition in the diversity, stability, and functional structure of microbial communities.
Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
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- Global epistasis in ecosystems arises from resource constraints.bioRxiv : the preprint server for biology · 2026Article
- Energetic constraints shape the diversity of feasible ecological networks.PLoS computational biology · 2026Article
- Fitness advantage of sequential metabolic strategies emerges from community interactions in strongly fluctuating environments.PLoS computational biology · 2026Article
- The network structure of cross-feeding impacts microbial community diversity under growth-inhibiting stresses.Nature communications · 2026Article
- Quantifying the contribution of the rare biosphere and functional potential to the compacted clay baseliner of sanitary landfill.World journal of microbiology & biotechnology · 2026Article
- Emergent frequency-dependent selection predicts mutation outcomes in complex ecological communities.bioRxiv : the preprint server for biology · 2026Article
- Mathematical Modelling and Intuition in Microbiology: A Perspective.Environmental microbiology · 2026Review
- Metabolic transitions along a moisture gradient in a poly-extreme high-altitude desert ecosystem within the Atacama Desert.Environmental microbiome · 2026Article
- The assembly of microbial communities on red sandstone surfaces was shaped by dispersal limitation and heterogeneous selection.mSystems · 2026Article
- Eco-evolutionary dynamics and environmental detoxification jointly shape bacterial community response to antibiotic perturbation.The ISME journal · 2026Article
- Environmental selection constrains metabolic network architecture despite taxonomic turnover in anaerobic digestion communities.The ISME journal · 2026Article
- Shipped and shifted: modeling collection-induced bias in microbiome multi-omics using a tractable fermentation system.NPJ biofilms and microbiomes · 2026Article
- Exploring cooperation among social pathogens: a computational perspective.FEMS microbiology reviews · 2026Review
- N2SIMBA: from Network topology to SIMulation of interactions and BActerial abundance, using microbial consumer resource model.Frontiers in bioinformatics · 2026Article
- Experimental evolution in an era of molecular manipulation.Nature reviews. Genetics · 2026Review
- A theory of ecological invasions and its implications for eco-evolutionary dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Modelling the prebiotic origins of regulation and agency in evolving protocell ecologies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- A theory of ecological invasions and its implications for eco-evolutionary dynamics.bioRxiv : the preprint server for biology · 2025Article
33 more citing papers are in PubMed but not listed here.
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6 authors.
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Abstract
A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences between the microbes and their chemical environment through the consumption and production of metabolites. By analyzing a generalized consumer resource model that explicitly includes cross-feeding, stochastic colonization, and thermodynamics, we show that complex microbial communities generically exhibit a transition as a function of available energy fluxes from a "resource-limited" regime where community structure and stability is shaped by energetic and metabolic considerations to a diverse regime where the dominant force shaping microbial communities is the overlap between species' consumption preferences. These two regimes have distinct species abundance patterns, different functional profiles, and respond differently to environmental perturbations. Our model reproduces large-scale ecological patterns observed across multiple experimental settings such as nestedness and differential beta diversity patterns along energy gradients. We discuss the experimental implications of our results and possible connections with disorder-induced phase transitions in statistical physics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.