Evidence map›Paper›PMID 30720720›Full record

ArticleMolecules (Basel, Switzerland)2019

New Anti-inflammatory Flavonol Glycosides from Lindera akoensis Hayata.

Chung-Ping Yang, Pei-Hsin Shie, Guan-Jhong Huang, Shih-Chang Chien, Yueh-Hsiung Kuo

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Anti-Aging Constituents fromMolecules (Basel, Switzerland) · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chung-Ping YangKey Laboratory of Preventive Veterinary Medicine and Biotechnology, Longyan University,Longyan 364012, China. cpyang218@gmail.com.
Pei-Hsin ShieKey Laboratory of Preventive Veterinary Medicine and Biotechnology, Longyan University,Longyan 364012, China. sps0220@gmail.com.
Guan-Jhong HuangDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University,Taichung 404, Taiwan. gjhuang@mail.cmu.edu.tw.
Shih-Chang ChienThe Experimental Forest Management Office, National Chung-Hsing University, Taichung 402, Taiwan. scchien@nchu.edu.tw.
Yueh-Hsiung KuoDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University,Taichung 404, Taiwan. kuoyh@mail.cmu.edu.tw.ORCID 0000-0001-5935-6755

Funding

China Medical University under the Aim for Top University Plan of the Ministry of Education CHM 106-4China Medical University under the Aim for Top University Plan of the Ministry of Education CHM 106-5-2Ministry of Health and Welfare MOHW106-TDU-B-212-113004
6 · The paper itself

Abstract

Inflammation is related to many diseases. Lindera akoensis Hayata was often used in folktherapy in Taiwan for inflammation. In this study, three new flavonol acyl glycosides, namelykaempferol-3-O--D-4",6"-di-(E)-p-coumaroylglucoside (1), 3"-(E)-p-coumaroylafzelin (2) and 40-Omethyl-2",4"-di-(E)-p-coumaroylquercitrin (3), and three components, 3-dodecyl-4-hydroxy-5-methyldihydrofuran-2-one (4), 2-acetoxyclovan-9-ol (5), (1,4,6)-trihydroxyeudesmane(6) that were isolated from the natural product for the first time were obtained along with 25 knowncompounds from L. akoensis. Their structures were determined by comprehensive spectroscopicanalyses (1D and 2D NMR, EI-, ESI- and HRESI-MS). The ability of 1 to decrease the LPS-stimulatedproduction of nitrite in RAW264.7 cell was evaluated, showing an IC

Indexed as

AnimalsAnti-Inflammatory AgentsFlavonolsGlycosidesLinderaMagnetic Resonance SpectroscopyMiceMolecular StructureRAW 264.7 CellsStructure-Activity RelationshipAnti-Inflammatory AgentsFlavonolsGlycosidesanti-inflammatoryflavonol glycosideLindera akoensis

Identifiers

PMID30720720
PMCPMC6384965

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.