Evidence map›Paper›PMID 30720338›Full record

ArticleDiabetes technology & therapeutics2019

Participants' Experiences of, and Views About, Daytime Use of a Day-and-Night Hybrid Closed-Loop System in Real Life Settings: Longitudinal Qualitative Study.

Julia Lawton, Maxine Blackburn, David Rankin, Janet M Allen, Fiona M Campbell, Lalantha Leelarathna, Martin Tauschmann, Hood Thabit, Malgorzata E Wilinska, Daniela Elleri and 1 more

Registry-linked trialOpen access · hybridAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes technology & therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05348499 (Mixed Methods Study Exploring the Impact of Hybrid Closed-loop Systems on Patient Reported Outcomes in People With Type I Diabetes and Their Partners), which is not on this map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05348499 unknown statusnot on this mapstarted 2021, after this paper: background citation

Mixed Methods Study Exploring the Impact of Hybrid Closed-loop Systems on Patient Reported Outcomes in People With Type I Diabetes and Their Partners

TypeobservationalSponsorUniversity of LeicesterRan2021 to 2023Enrolled350ConditionsType 1 Diabetes, Insulin Pump Therapy, Patient Reported OutcomesArmsQuestionnaire/Interview
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

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  18. A Systematic Review of Commercial Hybrid Closed-Loop Automated Insulin Delivery Systems.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023 · on this map
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Julia Lawton1 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.
Maxine Blackburn1 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.
David Rankin1 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.
Janet M Allen2 Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Fiona M Campbell4 Leeds Children's Hospital, Leeds, United Kingdom.
Lalantha Leelarathna5 Manchester Diabetes Center, Manchester Academic Health Science Center, Manchester University NHS Foundation Trust, University of Manchester, Manchester, United Kingdom.
Martin Tauschmann2 Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Hood Thabit5 Manchester Diabetes Center, Manchester Academic Health Science Center, Manchester University NHS Foundation Trust, University of Manchester, Manchester, United Kingdom.
Malgorzata E Wilinska2 Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Daniela Elleri6 Royal Hospital for Sick Children, Edinburgh, United Kingdom.
Roman Hovorka2 Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
University of Edinburgh · GBWellcome Trust · GBLeeds Teaching Hospitals NHS Trust · GBRoyal Hospital for Sick Children · GBUniversity of Cambridge · GBWellcome/MRC Institute of Metabolic Science · GB

Funding

Department of Health 14/23/09Wellcome Trust 100574/Z/12/Z
6 · The paper itself

Abstract

objectiveTo explore individuals' experiences of daytime use of a day-and-night hybrid closed-loop system, their information and support needs, and their views about how future systems could be improved. RESEARCH DESIGN AND

methodsTwenty-four adults, adolescents, and parents were interviewed before using a hybrid day-and-night closed-loop system and 3 months later, data were analyzed thematically.

resultsParticipants praised the closed loop's ability to respond to high and low blood glucose in ways which extended beyond their own capabilities and to act as a safety net and mop up errors, such as when a mealtime bolus was forgotten or unplanned activity was undertaken. Participants also described feeling less burdened by diabetes as a consequence and more able to lead flexible, spontaneous lives. Contrary to their initial expectations, and after trust in the system had been established, most individuals wanted opportunities to collaborate with the closed loop to optimize its effectiveness. Such individuals expressed a need to communicate information, such as when routines changed or to indicate different intensities of physical activity. While individuals valued frequent contact with staff in the initial month of use, most felt that their long-term support needs would be no greater than when using an insulin pump.

conclusionsWhile participants reported substantial benefits to using the closed loop during the day, they also identified ways in which the technology could be refined and education and training tailored to optimize effective use. Our findings suggest that mainstreaming this technology will not necessarily lead to increased demands on clinical staff.

Indexed as

AdolescentAdultBlood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1FemaleHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsLongitudinal StudiesMaleMiddle AgedParentsPatient Acceptance of Health CareQualitative ResearchBlood GlucoseHypoglycemic AgentsInsulinArtificial pancreasClosed-loop systemMedical deviceQualitative researchType 1 diabetesUser experience

Identifiers

PMID30720338
PMCPMC6434584
OpenAlexW2911860991

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.