Evidence map›Paper›PMID 30719960›Full record

ArticleInternational psychogeriatrics2019

Distinct age-related associations for body mass index and cognition in cognitively healthy very old veterans.

James Schmeidler, Cecilia N Mastrogiacomo, Michal S Beeri, Clive Rosendorff, Jeremy M Silverman

Open access · diamondAbstract read
In one paragraph

Article in International psychogeriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Stability in BMI over time is associated with a better cognitive trajectory in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

James SchmeidlerDepartment of Psychiatry,Icahn School of Medicine at Mount Sinai,New York, NY,USA.
Cecilia N MastrogiacomoCarnegie Mellon University,Pittsburgh, PA,USA.
Michal S BeeriDepartment of Psychiatry,Icahn School of Medicine at Mount Sinai,New York, NY,USA.
Clive RosendorffResearch & Development Service, James J. Peters Veterans Affairs Medical Center,Bronx, NY,USA.
Jeremy M SilvermanDepartment of Psychiatry,Icahn School of Medicine at Mount Sinai,New York, NY,USA.
Icahn School of Medicine at Mount Sinai · USCarnegie Mellon University · USJames J. Peters VA Medical Center · USSheba Medical Center · IL

Funding

QUANTITATIVE ANALYSIS OF MICROVASCULAR CHANGES IN THE AGING BRAINP01AG002219 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI HAROUTUNIAN, VAHRAM · 1985 to 2009
$19.2M
Cardiovascular RF and Successful Cognitive Aging in Very Old Male VeteransI01CX000900 · VA · JAMES J PETERS VA MEDICAL CENTER · PI SILVERMAN, JEREMY M. · 2014 to 2019
–
CSRD VA I01 CX000900NIA NIH HHS P01 AG002219
6 · The paper itself

Abstract

ABSTRACTAssociations between high body mass index (BMI) and subsequent cognitive decline, reported in elderly averaging below age 75, become less consistent at older ages. We compared the associations of BMI with cognition in moderately old (ages 75-84, N = 154) and oldest-old (85+, N = 93) samples. BMI and cognition were assessed cross-sectionally in cognitively intact elderly (mean age = 84.5, SD = 4.4) male veterans. Regression analyses of three cognitive domains - executive functions/language, attention, and memory-compared relationship with BMI between the moderately old and oldest-old. Higher BMI was associated with relatively poorer executive functions/language performance in the moderately old, while the opposite relationship, higher BMI associated with relatively better performance, was found in the oldest-old. Associations for the other two cognitive domains did not differ significantly between age groups. The reversal of association direction for executive functions/language performance with higher BMI is consistent with the protected survivor model. This model posits a minority subpopulation with a protective factor-genetic or otherwise-against both mortality and cognitive decline associated with risk factor status. The very old who remain cognitively intact despite the presence of risk factors are more likely to possess protection.

Indexed as

Body Mass IndexCognitionAgedAged, 80 and overAgingAttentionCognitive DysfunctionCross-Sectional StudiesExecutive FunctionFemaleHumansLanguageMaleMemoryNeuropsychological TestsRegression Analysisbody mass indexdementiaoldest-oldprotected survivorsuccessful cognitive aging

Identifiers

PMID30719960
PMCPMC6625833
OpenAlexW2912883833

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.