Evidence map›Paper›PMID 30719879›Full record

ReviewJournal of biomedical optics2019

Early diagnosis of traumatic intracranial hematomas.

Hasan Ayaz, Meltem Izzetoglu, Kurtulus Izzetoglu, Banu Onaral, Baruch Ben Dor

Open access · goldAbstract readReview
In one paragraph

Review in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  4. Prehospital technologies for early stroke detection - A review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  13. Advances in cost-effective integrated spectrometers.Light, science & applications · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hasan AyazDrexel University, School of Biomedical Engineering, Science and Health Systems, Philadelphia, Penns, United States.
Meltem IzzetogluDrexel University, School of Biomedical Engineering, Science and Health Systems, Philadelphia, Penns, United States.
Kurtulus IzzetogluDrexel University, School of Biomedical Engineering, Science and Health Systems, Philadelphia, Penns, United States.
Banu OnaralDrexel University, School of Biomedical Engineering, Science and Health Systems, Philadelphia, Penns, United States.
Baruch Ben DorInfrascan Inc., Philadelphia, Pennsylvania, United States.
Drexel University · USInfrascan (United States) · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Timing of the intervention for intracranial hematomas is critical for its success, specifically since expansion of the hemorrhage can result in debilitating and sometimes fatal outcomes. Led by Britton Chance, we and an extended team from University of Pennsylvania, Baylor and Drexel universities developed a handheld brain hematoma detector for early triage and diagnosis of head trauma victims. After obtaining de novo Food and Drug Administration clearance, over 200 systems are deployed in all Marine battalion aid stations around the world. Infrascanner, a handheld brain hematoma detection system, is based on the differential near-infrared light absorption of the injured versus the noninjured part of brain. About 12 independent studies have been conducted in the USA, Canada, Spain, Italy, the Netherlands, Germany, Russia, Poland, Afghanistan, India, China, and Turkey. Here, we outline the background and design of the device as well as clinical studies with a total of 1293 patients and 203 hematomas. Infrascanner demonstrates high sensitivity (adults: 92.5% and children: 93%) and specificity (adults: 82.9% and children: 86.5%) in detecting intracranial hematomas >3.5  mL in volume and <2.5  cm from the surface of the brain. Infrascanner is a clinically effective screening solution for head trauma patients in prehospital settings where timely triage is critical.

Indexed as

Clinical Trials as TopicEmergency Medical ServicesEquipment DesignHematoma, Epidural, CranialHematoma, SubduralHumansIntracranial Hemorrhage, TraumaticPoint-of-Care SystemsPredictive Value of TestsReproducibility of ResultsSpectroscopy, Near-InfraredTrauma Severity IndicesUser-Computer Interfaceepiduralhematomamedical devicenear-infrared spectroscopysubduraltraumatic brain injury

Identifiers

PMID30719879
PMCPMC6992895
OpenAlexW2913307894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.