Evidence map›Paper›PMID 30719648›Full record

ArticleObesity surgery2019

Bone Health in Patients with Type 2 Diabetes Treated by Roux-En-Y Gastric Bypass and the Role of Diabetes Remission.

Lene Ring Madsen, Rasmus Espersen, Marie Juul Ornstrup, Niklas Rye Jørgensen, Bente Lomholt Langdahl, Bjørn Richelsen

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04174495 (Bone Fragility Evaluation by Dual X-Ray Absorptiometry), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04174495 completednot on this mapstarted 2020, after this paper: background citation

Bone Fragility Evaluation by Dual X-Ray Absorptiometry (DXA) and CT-scan (vertebral Fracture and Scanographic Bone Attenuation Coefficient of the First Lumbar Vertebra SBAC-L1) in Obese Patients

TypeobservationalSponsorCentral Hospital, Nancy, FranceRan2020 to 2021Enrolled1,500ConditionsObesity, Bariatric Surgery CandidateArmsDXA and CT-scan
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Diabetes and bone.Osteoporosis and sarcopenia · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lene Ring MadsenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark. leemas@rm.dk.ORCID 0000-0002-8964-9564
Rasmus EspersenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Marie Juul OrnstrupDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Niklas Rye JørgensenDepartment of Clinical Biochemistry, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Bente Lomholt LangdahlDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Bjørn RichelsenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Aarhus University · DKAarhus University Hospital · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRoux-en-Y gastric bypass (RYGB) has been associated with negative effects on bone. Whether this association is affected by pre-surgical type 2 diabetes (T2D) and surgically induced diabetes remission is unknown.

methodsIn this cross-sectional, matched cohort study 6 years after RYGB, we investigated bone health in 96 individuals with body mass index (BMI) > 35 kg/m

resultsThe RYGB group had lower hip (0.916 vs 1.010 g/cm

conclusionsIndividuals with T2D treated by RYGB, compared to individuals with T2D of similar age and body composition not treated by RYGB, have lower BMD, lower bone strength, and increased levels of several bone turnover markers. Bone health was not associated with current diabetes status in the RYGB group.

Indexed as

Diabetes Mellitus, Type 2Absorptiometry, PhotonBody Mass IndexBone DensityBone Diseases, MetabolicCohort StudiesCross-Sectional StudiesFemaleGastric BypassHumansMaleMiddle AgedObesity, MorbidPostoperative PeriodRemission InductionBariatric surgeryBone turnoverDiabetesDual-energy X-ray absorptiometryHigh-resolution peripheral quantitative computed tomographyOsteoporosisRoux-en-Y gastric bypassType 2 diabetes

Identifiers

PMID30719648
OpenAlexW2912834003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.