ArticleProbiotics and antimicrobial proteins2020
The Quorum Quenching Bacterium Bacillus licheniformis T-1 Protects Zebrafish against Aeromonas hydrophila Infection.
Article in Probiotics and antimicrobial proteins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 66 citations in OpenAlex.
- The Invisible Balance: How Prebiotics and Probiotics Can Support Fish Health and Development.Life (Basel, Switzerland) · 2026Review
- Gut Microbiota Divergence Drives Aeromonas Hydrophila Resistance in Common Carp (Cyprinus carpio): Probiotic Role of Cetobacterium.Probiotics and antimicrobial proteins · 2026Article
- The chemotaxis disruption of Aeromonas veronii by Lactococcus lactis and its probiotic effect on loach (Misgurnus anguillicaudatus).Archives of microbiology · 2026Article
- Lactiplantibacillus Plantarum O126 Postbiotics Boost growth, Antioxidant levels, Disease resistance, and Gut Health in Sea Cucumber (Apostichopus japonicus).Probiotics and antimicrobial proteins · 2026Article
- Antagonistic Mechanisms of Probiotic Aliivibrio sp. Strain Vl2 Against Moritella viscosa: Evidence from Co-cultivation and Targeted Transcriptomic Analysis.Probiotics and antimicrobial proteins · 2026Article
- Probiotics: multifunctional microorganisms for human health and biotechnological applications.Frontiers in microbiology · 2026Review
- Feeding Strategies with Multi-Strain Probiotics Affect Growth, Health Condition, and Disease Resistance in Asian Seabass (Lates calcarifer).Probiotics and antimicrobial proteins · 2025Article
- Review
- Quorum Quenching Approaches against Bacterial-Biofilm-Induced Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2024Review
- An In-Depth Study on the Inhibition of Quorum Sensing byMicroorganisms · 2024Article
- Antimicrobial resistance in aeromonads and new therapies targeting quorum sensing.Applied microbiology and biotechnology · 2024Review
- Microbial feed additives in ruminant feeding.AIMS microbiology · 2024Review
- Efficacy of ceftiofur N-acyl homoserine lactonase niosome in the treatment of multi-resistant Klebsiella pneumoniae in broilers.Veterinary research communications · 2023Article
- Selection and Molecular Response of AHL-lactonase (aiiA) Producing Bacillus sp. Under Penicillin G-induced Conditions.The protein journal · 2023Article
- Exploring the Function of Quorum Sensing Regulated Biofilms in Biological Wastewater Treatment: A Review.International journal of molecular sciences · 2022Review
- Quorum Quenching Strains Isolated from the Microbiota of Sea Anemones and Holothurians AttenuateMicroorganisms · 2022Article
- Quorum-Sensing Inhibition by Gram-Positive Bacteria.Microorganisms · 2022Review
- Article
- Attenuation ofAntibiotics (Basel, Switzerland) · 2021Article
- Mechanisms Used by Probiotics to Confer Pathogen Resistance to Teleost Fish.Frontiers in immunology · 2021Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quorum sensing, bacterial cell-to-cell communication via small signaling molecules regulates virulence in many bacterial pathogens, and is a promising target for antivirulence therapy, which may inhibit virulence rather than cell growth and division. Herein, Bacillus strains capable of degrading QS molecules from freshwater environments were screened as potential aquaculture probiotics. A total of 34 Bacillus strains were isolated. Strain T-1 was selected with "H" streaking and double layer agar plate methods using Chromabacterium violaceum ATCC12472 as reporter, and eventually identified as Bacillus licheniformis based on biochemical and molecular identification. Quorum quenching by T-1 was confirmed using C. violaceum CV026. T-1 was non-hemolytic in vitro. In biocontrol experiments, T-1 reduced the pathogenicity of Aeromonas hydrophila cb15 in zebrafish co-injected intraperitoneally with both strains, achieving a relative percentage survival of 70%. Determination and analysis of the T-1 draft genome using the Illumina Hiseq 2500 platform identified the quorum quenching gene ytnP, encoding an acyl-homoserine lactone metallo-β-lactamase, as a potential QS quencher in T-1. In conclusion, B. licheniformis T-1 could be a safe and effective quorum quenching bacterium for protecting hosts against pathogenic bacterial infections in aquaculture.
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