Evidence map›Paper›PMID 30719587›Full record

ArticleJournal of digital imaging2019

Automatic Nasopharyngeal Carcinoma Segmentation Using Fully Convolutional Networks with Auxiliary Paths on Dual-Modality PET-CT Images.

Lijun Zhao, Zixiao Lu, Jun Jiang, Yujia Zhou, Yi Wu, Qianjin Feng

Abstract read
In one paragraph

Article in Journal of digital imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  4. Review
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  6. Multi-scale brain tumor segmentation combined with deep supervision.International journal of computer assisted radiology and surgery · 2022
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  11. Changes of [BMC medical imaging · 2021
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  12. Artificial intelligence in molecular imaging.Annals of translational medicine · 2021
    Review
  13. Article
  14. Application and Construction of Deep Learning Networks in Medical Imaging.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. A Review of Artificial Intelligence Application for Radiotherapy.Dose-response : a publication of International Hormesis Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lijun ZhaoSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Zixiao LuSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Jun JiangSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Yujia ZhouSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Yi WuSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Qianjin FengSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China. qianjinfeng08@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is prevalent in certain areas, such as South China, Southeast Asia, and the Middle East. Radiation therapy is the most efficient means to treat this malignant tumor. Positron emission tomography-computed tomography (PET-CT) is a suitable imaging technique to assess this disease. However, the large amount of data produced by numerous patients causes traditional manual delineation of tumor contour, a basic step for radiotherapy, to become time-consuming and labor-intensive. Thus, the demand for automatic and credible segmentation methods to alleviate the workload of radiologists is increasing. This paper presents a method that uses fully convolutional networks with auxiliary paths to achieve automatic segmentation of NPC on PET-CT images. This work is the first to segment NPC using dual-modality PET-CT images. This technique is identical to what is used in clinical practice and offers considerable convenience for subsequent radiotherapy. The deep supervision introduced by auxiliary paths can explicitly guide the training of lower layers, thus enabling these layers to learn more representative features and improve the discriminative capability of the model. Results of threefold cross-validation with a mean dice score of 87.47% demonstrate the efficiency and robustness of the proposed method. The method remarkably outperforms state-of-the-art methods in NPC segmentation. We also validated by experiments that the registration process among different subjects and the auxiliary paths strategy are considerably useful techniques for learning discriminative features and improving segmentation performance.

Indexed as

Neural Networks, ComputerPositron Emission Tomography Computed TomographyAutomationHumansImaging, Three-DimensionalNasopharyngeal CarcinomaRadiographic Image Interpretation, Computer-AssistedFully convolutional neural networksNasopharyngeal carcinomaPET-CTSegmentation

Identifiers

PMID30719587
PMCPMC6499852

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.