Evidence map›Paper›PMID 30719466›Full record

ArticleBulletin of emergency and trauma2019

Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol.

Antonio Brillantino, Francesca Iacobellis, Patrizio Festa, Arianna Mottola, Ciro Acampora, Fabio Corvino, Santolo Del Giudice, Michele Lanza, Mariano Armellino, Raffaella Niola and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Bulletin of emergency and trauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Liver trauma: WSES 2020 guidelines.World journal of emergency surgery : WJES · 2020
    Guideline
  4. The effect of silibinin on liver healing following blunt trauma in rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Is it possible to predict mortality in patients with high-grade blunt liver injury? A single trauma center study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Antonio BrillantinoDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Francesca IacobellisDepartment of Radiology, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Patrizio FestaDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Arianna MottolaDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Ciro AcamporaDepartment of Radiology, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Fabio CorvinoInterventional Radiology Department, A Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Santolo Del GiudiceDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Michele LanzaDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Mariano ArmellinoDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Raffaella NiolaInterventional Radiology Department, A Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Luigia RomanoDepartment of Radiology, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Maurizio CastriconiDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Maurizio De PalmaDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Giuseppe NoscheseDepartment of Surgery, A. Cardarelli Hospital, Via A. Cardarelli 9 80131 Naples, Italy.
Ospedale Antonio Cardarelli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the safety and effectiveness of NOM (non-operative management) in the treatment of blunt liver trauma, following a standardized treatment protocol.

methodsAll the hemodynamically stable patients with computed tomography (CT) diagnosis of blunt liver trauma underwent NOM. It included strict clinical and laboratory observation, 48-72h contrast enhanced ultrasonography (CEUS) or CT follow-up, a primary angioembolization in case of admission CT evidence of vascular injuries and a secondary angioembolization in presence of vascular injuries signs at follow-up CEUS.

results181 patients (85.4%) [55 (30.4%) women and 126 (69.6%) men, median age 39 (range 14-71)] were included. Of these, 63 patients (34.8%) had grade I, 48 patients (26.5%) grade II, 39 patients (21.5%) grade III, 21 patients (11.6%) grade IV and 10 patients (5.5%) grade V liver injuries. The overall success rate of NOM was 96.7% (175/181). There was not significant difference in the success rate between the patients with different liver injuries grade. Morbidity rate was 7.4% (13/175). Major complications (2 bilomas, 1 liver hematoma and 2 liver abscesses) were successfully treated by CEUS or CT guided drainage. Eighteen (18/181) patients (9.9%) underwent angioembolization with successful results.

conclusionNon-operative management of blunt liver trauma represents a safe and effective treatment for both minor and severe injuries, achieving an high success rate and an acceptable morbidity rate. The angiographic study with embolization, although required only in selected cases of vascular injuries, represents a fundamental therapeutic option in a significant percentage of patients.

Indexed as

AngioembolizationBlunt traumaHepatic traumaLiver injuryNon-operative management

Identifiers

PMID30719466
PMCPMC6360015
OpenAlexW2907119392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.