ArticleBioMed research international2019
The Ovotransferrin-Derived Peptide IRW Attenuates Lipopolysaccharide-Induced Inflammatory Responses.
Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Ovotransferrin in Foods: Digestive Stability, Cross-Matrix Interactions, and Targeted Applications.Foods (Basel, Switzerland) · 2026Review
- Egg Powder Fortification of Tom Brown Significantly Improves Hemoglobin and Ferritin and Reduces Inflammation Among School-Aged Children in Ghana: A Randomized Controlled Trial.Nutrition and metabolic insights · 2026Article
- Ovotransferrin as a Multifunctional Bioactive Protein: Unlocking Its Potential in Animal Health and Wellness.Veterinary sciences · 2025Review
- Hen egg white bovine colostrum supplement reduces symptoms of mild/moderate COVID-19: a randomized control trial.Future science OA · 2023Article
- A Comparative Study on the Effects of Different Sources of Carboxymethyl Poria Polysaccharides on the Repair of DSS-Induced Colitis in Mice.International journal of molecular sciences · 2023Article
- Article
- Transcriptomics Changes in the Peritoneum of Mice with Lipopolysaccharide-Induced Peritonitis.International journal of molecular sciences · 2021Article
- Enzymatic Hydrolysis of Ovotransferrin and the Functional Properties of Its Hydrolysates.Food science of animal resources · 2021Article
- Effects of IQW and IRW on Inflammation and Gut Microbiota in ETEC-Induced Diarrhea.Mediators of inflammation · 2021Article
- A Polyol-Polyol Super-Carbon-Chain Compound Containing Thirty-Six Carbon Stereocenters from the DinoflagellateMarine drugs · 2020Article
- The Potential of Food Protein-Derived Bioactive Peptides against Chronic Intestinal Inflammation.Mediators of inflammation · 2020Review
- Egg Protein Transferrin-Derived Peptides IRW and IQW RegulateFrontiers in microbiology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IRW (Ile-Arg-Trp), a bioactive peptide isolated from egg ovotransferrin, has been shown to exert anti-inflammatory effects. In this study, the effects of IRW on inflammatory cytokines and microbiota were explored in human umbilical vein endothelial cells (HUVECs) and a lipopolysaccharide (LPS)-induced rat model of inflammatory peritonitis. Rats were injected intraperitoneally with LPS to establish peritonitis. HUVECs were exposed to IRW for 12 h before introducing LPS. Notably, IRW exerted beneficial effects against LPS-induced peritonitis, specifically, by reducing the serum levels of tumour necrosis factor (TNF)-
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