Evidence map›Paper›PMID 30719243›Full record

ArticleJournal of market access & health policy2019

Perspectives to mitigate payer uncertainty in health technology assessment of novel oncology drugs.

Oriol Solà-Morales, Timm Volmer, Lorenzo Mantovani

Abstract readEditorial
In one paragraph

Article in Journal of market access & health policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Oriol Solà-MoralesHealth Innovation Technology Transfer and International, University of Catalonia, Barcelona, Spain.
Timm VolmerSmartStep Consulting GmbH, Hamburg, Germany.ORCID 0000-0002-4054-2563
Lorenzo MantovaniCentre for Public Health Research, University of Milan-Bicocca, Milan, Italy.ORCID 0000-0003-3866-8199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reimbursement decisions on new oncology drugs are now often made while uncertainty remains about a drug's risk-benefit profile. One consequence of this is a delay in patient access to valuable new medicines. We share our perspectives on strategies to mitigate sources of uncertainty in the health technology assessment process. These include flexible approaches for evaluating the additional benefit, such as better use of surrogate endpoints and health-related quality of life data, and renewed research efforts to define the optimal target population and generate real-world evidence post-authorisation.

Indexed as

Health Related Quality of Life (HRQoL)HTAOncologypatient accessreimbursementsurrogate endpoint

Identifiers

PMID30719243
PMCPMC6346722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.