ArticleJournal of Cancer2019
Systemic inflammation score predicts survival in patients with intrahepatic cholangiocarcinoma undergoing curative resection.
Article in Journal of Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Prognostic utility of preoperative inflammatory markers in patients with intrahepatic cholangiocarcinoma after hepatic resection: A systematic review and meta-analysis.Cancer medicine · 2023Pooled it
- The prognostic value of neutrophil-to-lymphocyte ratio in cholangiocarcinoma: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Pooled it
- A Multicenter Study of Systemic Inflammatory Biomarkers for Prognostic Evaluation in iCCA Patients.Journal of inflammation research · 2025Article
- The prognostic impact of preoperative CA19-9 on resectable cholangiocarcinoma: a comprehensive systematic review and meta-analysis.Discover oncology · 2024Article
- Prognostic value of the Naples prognostic score in patients with intrahepatic cholangiocarcinoma after hepatectomy.BMC cancer · 2024Article
- Tumor Markers in Differential Diagnosis of Benign Ovarian Masses.International journal of women's health · 2024Article
- Prognostic impact of portal area inflammation on intrahepatic cholangiocarcinoma patients without lymph node metastasis.Journal of gastrointestinal oncology · 2023Article
- Preoperative neutrophil-to-lymphocyte ratio is prognostic for early recurrence after curative intrahepatic cholangiocarcinoma resection.Annals of hepato-biliary-pancreatic surgery · 2023Article
- Galectin-9 in Gastroenterological Cancer.International journal of molecular sciences · 2023Review
- A novel preoperative inflammation score system established for postoperative prognosis predicting of intrahepatic cholangiocarcinoma.BMC cancer · 2023Article
- Klatskin Tumor: A Survival Analysis According to Tumor Characteristics and Inflammatory Ratios.Medicina (Kaunas, Lithuania) · 2022Article
- Lymphocyte-to-Monocyte Ratio and Clinical Outcomes in Cholangiocarcinoma: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Review
- [Predictive value of prognostic inflammatory and tumor score in intrahepatic cholangiocarcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- Systematic Review and Meta-Analysis of Prognostic Factors for Early Recurrence in Intrahepatic Cholangiocarcinoma After Curative-Intent Resection.Annals of surgical oncology · 2022Review
- Predictive value of modified systemic inflammation score for postoperative unplanned ICU admission in patients with NSCLC.Frontiers in surgery · 2022Article
- Can the systemic inflammation score be used to predict prognosis in gastric cancer patients undergoing surgery? A systematic review and meta-analysis.Frontiers in surgery · 2022Review
- Controlling nutritional status score as a prognostic marker to predict overall survival in resected biliary tract cancers.Annals of translational medicine · 2021Article
- Prognostic Value of Inflammatory and Tumour Markers in Small-Duct Subtype Intrahepatic Cholangiocarcinoma after Curative-Intent Resection.Gastroenterology research and practice · 2021Article
- Evaluation of Preoperative Inflammation-Based Prognostic Scores in Patients With Intrahepatic Cholangiocarcinoma: A Multicenter Cohort Study.Frontiers in oncology · 2021Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammation has a critical role in the development and progression of cancers. We developed a novel systemic inflammation score (SIS) based on lymphocyte, monocyte, and CA19-9 and explored its prognostic value in intrahepatic cholangiocarcinoma (ICC). From January 2005 to December 2011, 322 consecutive ICC patients who underwent curative resection in our center were included in this study, and validated in a retrospective study of 126 patients enrolled from 2012 to 2014. Clinicopathological variables including preoperative serum CA19-9 and LMR were analyzed. The cutoff values of CA19-9 and LMR were determined based on receiver operating characteristics curve analysis in the primary cohort. Kaplan-Meier curves and multivariate Cox-regression analyses were calculated for time to recurrence (TTR) and overall survival (OS). In univariate analysis of all patients, all three inflammatory and tumor marker including NLR ≥ 2.49 (
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