Evidence map›Paper›PMID 30719069›Full record

ArticleComputational and mathematical methods in medicine2019

Patient-Specific Phantomless Estimation of Bone Mineral Density and Its Effects on Finite Element Analysis Results: A Feasibility Study.

Young Han Lee, Jung Jin Kim, In Gwun Jang

Open access · hybridAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

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  3. Assessment of trabecular bone Hounsfield units in the lumbar spine for osteoporosis evaluation in individuals aged 65 and above: a review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Young Han LeeDepartment of Radiology, College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Yonsei University College of Medicine, Republic of Korea.ORCID 0000-0002-5602-391X
Jung Jin KimThe Cho Chun Shik Graduate School of Green Transportation, 291, Daehak-ro, Yuseong-gu, Daejeon 34141, Korea Advanced Institute of Science and Technology, Republic of Korea.ORCID 0000-0001-6948-6027
In Gwun JangThe Cho Chun Shik Graduate School of Green Transportation, 291, Daehak-ro, Yuseong-gu, Daejeon 34141, Korea Advanced Institute of Science and Technology, Republic of Korea.ORCID 0000-0002-5250-1208
Korea Advanced Institute of Science and Technology · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study proposes a regression model for the phantomless Hounsfield units (HU) to bone mineral density (BMD) conversion including patient physical factors and analyzes the accuracy of the estimated BMD values.

methodsThe HU values, BMDs, circumferences of the body, and cross-sectional areas of bone were measured from 39 quantitative computed tomography images of L2 vertebrae and hips. Then, the phantomless HU-to-BMD conversion was derived using a multiple linear regression model. For the statistical analysis, the correlation between the estimated BMD values and the reference BMD values was evaluated using Pearson's correlation test. Voxelwise BMD and finite element analysis (FEA) results were analyzed in terms of root-mean-square error (RMSE) and strain energy density, respectively.

resultsThe HU values and circumferences were statistically significant (

conclusionsThe proposed phantomless HU-to-BMD conversion demonstrates the potential of precisely estimating BMD values from CT images without the reference phantom and being utilized as a viable tool for FEA-based quantitative assessment using routine CT images.

Indexed as

Bone DensityAdultAgedAlgorithmsElastic ModulusFeasibility StudiesFemaleFemurFinite Element AnalysisHumansImaging, Three-DimensionalLumbar VertebraeMaleMiddle AgedPatient-Specific ModelingPelvic Bones

Identifiers

PMID30719069
PMCPMC6335860
OpenAlexW2908316022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.