Evidence map›Paper›PMID 30719021›Full record

ArticleFrontiers in neurology2018

Alzheimer's "Prevention" vs. "Risk Reduction": Transcending Semantics for Clinical Practice.

John F Hodes, Carlee I Oakley, James H O'Keefe, Peilin Lu, James E Galvin, Nabeel Saif, Sonia Bellara, Aneela Rahman, Yakir Kaufman, Hollie Hristov and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Cognitive Resilience in Brain Health and Dementia Research.Journal of Alzheimer's disease : JAD · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Individualized clinical management of patients at risk for Alzheimer's dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2019
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 4 countries.

John F HodesThe Klingler College of Arts and Sciences, Marquette University, Milwaukee, WI, United States.
Carlee I OakleyKansas City School of Medicine, University of Missouri, Kansas City, MO, United States.
James H O'KeefeSaint Luke's of Kansas City Mid America Heart Institute, Kansas City, MO, United States.
Peilin LuDepartment of Neurology, Zhejiang University School of Medicine, Hangzhou Shi, China.
James E GalvinComprehensive Center for Brain Health, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, United States.
Nabeel SaifWeill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY, United States.
Sonia BellaraWeill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY, United States.
Aneela RahmanWeill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY, United States.
Yakir KaufmanHerzog Hospital, Hebrew University, Jerusalem, Israel.
Hollie HristovWeill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY, United States.
Tarek K RajjiCentre for Addiction and Mental Health and University of Toronto, Toronto, ON, Canada.
Anne Marie Fosnacht MorganNorthShore University HealthSystem, Evanston, IL, United States.
Smita PatelNorthShore University HealthSystem, Evanston, IL, United States.
David A MerrillDepartment of Psychiatry, University of California, Los Angeles, Los Angeles, CA, United States.
Scott KaiserPacific Brain Health Center, Pacific Neuroscience Institute, Los Angeles, CA, United States.
Josefina Meléndez-CabreroDepartment of Neurology, Weill Cornell Medicine, San Juan, Puerto Rico.
Juan A MelendezJersey Memory Assessment Service, Health and Community Services, Jersey, United Kingdom.
Robert KrikorianDepartment of Psychiatry & Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Richard S IsaacsonWeill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY, United States.
Cornell University · USNew York Hospital Queens · USNewYork–Presbyterian Hospital · USNorthShore University HealthSystem · USPacific Heart Institute · USCentre for Addiction and Mental Health · CAFlorida Atlantic University · USHerzog Hospital · ILMarquette University · USSaint Luke's Hospital · USUniversity of Cincinnati Medical Center · USUniversity of Missouri–Kansas City · USZhejiang University · CN

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Timing of Menopausal Hormone Therapy across Perimenopause to Menopause Transition: Neuroimmune System in BrainP01AG026572 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROBERTA EILEEN BRINTON · 2006 to 2026
$53.7M
Multicultural Community Dementia Screening.R01AG040211 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GALVIN, JAMES E · 2011 to 2018
$3.2M
NCATS NIH HHS UL1 TR002384NIA NIH HHS P01 AG026572NIA NIH HHS R01 AG040211
6 · The paper itself

Abstract

The terms "prevention" and "risk reduction" are often used interchangeably in medicine. There is considerable debate, however, over the use of these terms in describing interventions that aim to

Indexed as

Alzheimer's disease preventiondementia preventionprecision medicineprimary preventionrisk reductionsecondary preventiontertiary prevention

Identifiers

PMID30719021
PMCPMC6348710
OpenAlexW2914208327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.