Evidence map›Paper›PMID 30719003›Full record

ArticleFrontiers in pharmacology2018

Protective Effects of Live Combined

Lisha Guo, Mei Meng, Yaping Wei, Feixue Lin, Ying Jiang, Xianzhen Cui, Guirong Wang, Chunting Wang, Xiaosun Guo

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07720232 (Effect of Bacillus Subtilis and Enterococcus Faecium Combination Therapy Combined With Conventional Lipid-Lowering Treatment on Triglyceride Levels in Patients With Hypertriglyceridemic Acute Pancreatitis), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07720232 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Bacillus Subtilis and Enterococcus Faecium Combination Therapy Combined With Conventional Lipid-Lowering Treatment on Triglyceride Levels in Patients With Hypertriglyceridemic Acute Pancreatitis: A Prospective Randomized Controlled Trial

TypeinterventionalSponsorJianyin ZhouRan2026 to 2029Enrolled180ConditionsHypertriglyceridemic Acute Pancreatitis, Acute Pancreatitis, Hypertriglyceridemia-induced, HyperlipidemiaArmsLive Combined Bacillus subtilis and Enterococcus faecium Enteric-coated Capsules (LCBE), Standard Care (in control arm)
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Food science & nutrition · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Effects of Live CombinedFrontiers in cellular and infection microbiology · 2022
    Article
  6. Article
  7. Article
  8. SupplementalJournal of immunology research · 2021
    Article
  9. Pharmacological Effects of Marine-DerivedBioMed research international · 2021
    Article
  10. Frontiers in cellular and infection microbiology · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Lisha GuoDepartment of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
Mei MengDepartment of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
Yaping WeiDepartment of Physiology and Pathophysiology, School of Basic Medicine, Shandong University, Jinan, China.
Feixue LinBinzhou Medical University Hospital, Binzhou, China.
Ying JiangSchool of Medicine, Shandong University, Jinan, China.
Xianzhen CuiSchool of Medicine, Shandong University, Jinan, China.
Guirong WangDepartment of Surgery, SUNY Upstate Medical University, Syracuse, NY, United States.
Chunting WangDepartment of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
Xiaosun GuoDepartment of Physiology and Pathophysiology, School of Basic Medicine, Shandong University, Jinan, China.
Shandong University · CNBinzhou University · CNShandong Provincial Hospital · CNSUNY Upstate Medical University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AKT pathwayCLP sepsislive combined Bacillus subtilis and Enterococcus faecium (LCBE) enteric-coated capsulesmacrophage activation and transformationmast cell degranulation

Identifiers

PMID30719003
PMCPMC6348999
OpenAlexW2913651677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.