Evidence map›Paper›PMID 30718984›Full record

ArticleContrast media & molecular imaging2019

Associations between Histogram Analysis Parameters Derived from DCE-MRI and Histopathological Features including Expression of EGFR, p16, VEGF, Hif1-alpha, and p53 in HNSCC.

Hans Jonas Meyer, Leonard Leifels, Gordian Hamerla, Anne Kathrin Höhn, Alexey Surov

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hans Jonas MeyerDepartment of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.ORCID 0000-0001-8489-706X
Leonard LeifelsDepartment of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Gordian HamerlaDepartment of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Anne Kathrin HöhnDepartment of Pathology, University of Leipzig, Leipzig, Germany.
Alexey SurovDepartment of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.ORCID 0000-0002-9273-3943
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Our purpose was to elucidate possible correlations between histogram parameters derived from dynamic contrast-enhanced MRI (DCE-MRI) with several histopathological features in head and neck squamous cell carcinomas (HNSCC). Methods: Thirty patients with primary HNSCC were prospectively acquired. Histogram analysis was derived from the DCE-MRI parameters: Results: Conclusion: DCE-MRI can reflect several histopathological features in HNSCC. Associations between DCE-MRI and histopathology in HNSCC depend on p16 status.

Indexed as

AdultAgedErbB ReceptorsFemaleHumansHypoxia-Inducible Factor 1, alpha SubunitMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesSquamous Cell Carcinoma of Head and NeckTumor Suppressor Protein p53Vascular Endothelial Growth Factor AEGFR protein, humanErbB ReceptorsHypoxia-Inducible Factor 1, alpha SubunitTumor Suppressor Protein p53Vascular Endothelial Growth Factor A

Identifiers

PMID30718984
PMCPMC6334376
OpenAlexW2906911426

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.