ArticleNature biotechnology2019
Resistance gene cloning from a wild crop relative by sequence capture and association genetics.
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Article in Nature biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers.
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180citing papers in PubMed
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Who cites it
180 citing papers in PubMed.
- Potential unlocked: an atlas of cloned wheat genes for genome engineering and breeding.The New phytologist · 2026Review
- An HMA-like integrated domain in the wheat tandem kinase WTK4 recognises an RNase-like pathogen effector.Nature communications · 2026Article
- Advances in gene cloning and functional genomics approaches for wheat (Triticum aestivum L.) improvement.The plant genome · 2026Review
- k-mer-based approaches to unlock genebank genomics for targeted crop improvement.Nature genetics · 2026Review
- Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance.The plant genome · 2026Review
- Phased potato genome assembly and association genetics enable delineation of the H1 resistance locus against potato cyst nematodes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Extensive phenotyping and genome-wide analysis of grain number-related traits in a diverse wheat core collection.The plant genome · 2026Article
- Genomics in wheat improvement: Progress and perspectives.The plant genome · 2026Review
- Accelerating Resistance Breeding: Emerging Methods to Identify and Validate Plant Immunity Genes.Plants (Basel, Switzerland) · 2026Review
- From gene-for-gene to NLRome-for-effectorome: decoding the dynamic interplay between phytopathogenic effector networks and plant immune systems.FEMS microbiology reviews · 2026Review
- Pan-NLRome ofFrontiers in plant science · 2026Article
- The Application of RenSeq for Pan-NLRome Analysis.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Virulence on Pm4 kinase-based resistance is determined by two divergent wheat powdery mildew effectors.Nature plants · 2026Article
- Article
- Editorial: Molecular selection of promising resistant genotypes to disease in cereal crops.Frontiers in plant science · 2026Article
- Genetic resource optimization: a core collection of tetraploid wheat from 2,254 NBRP-wheat accessions.BMC plant biology · 2025Article
- The pan-NLRome and diversity of Watkins wheat provide genetic resources for improving disease resistance and adaptation.Plant communications · 2025Article
- Harnessing primary, secondary and tertiary genepools for durable wheat disease resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Discovery of functional NLRs using expression level, high-throughput transformation and large-scale phenotyping.Nature plants · 2025Article
- Multiple effectors trigger non-host resistance in Solanum americanum against Pseudomonas syringae.The Plant journal : for cell and molecular biology · 2025Article
120 more citing papers are in PubMed but not listed here.
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Authors and funding
27 authors.
Sanu AroraJohn Innes Centre, Norwich Research Park, Norwich, UK.
Burkhard SteuernagelJohn Innes Centre, Norwich Research Park, Norwich, UK.
Kumar GauravJohn Innes Centre, Norwich Research Park, Norwich, UK.
Sutha ChandramohanCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, Australian Capital Territory, Australia.
Yunming LongDepartment of Plant Sciences, North Dakota State University, Fargo, ND, USA.
Oadi MatnyDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, USA.
Ryan JohnsonDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, USA.
Jacob EnkArbor Biosciences, Ann Arbor, MI, USA.
Sambasivam PeriyannanCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, Australian Capital Territory, Australia.
Narinder SinghWheat Genetics Resource Center, Department of Plant Pathology, Kansas State University, Manhattan, KS, USA.ORCID http://orcid.org/0000-0002-4370-8565
M Asyraf Md HattaJohn Innes Centre, Norwich Research Park, Norwich, UK.ORCID http://orcid.org/0000-0002-8952-5684
Naveenkumar AthiyannanCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, Australian Capital Territory, Australia.ORCID http://orcid.org/0000-0002-9232-4680
Jitender CheemaJohn Innes Centre, Norwich Research Park, Norwich, UK.
Guotai YuJohn Innes Centre, Norwich Research Park, Norwich, UK.
Ngonidzashe KangaraJohn Innes Centre, Norwich Research Park, Norwich, UK.
Sreya GhoshJohn Innes Centre, Norwich Research Park, Norwich, UK.ORCID http://orcid.org/0000-0002-7271-8914
Les J SzaboUS Department of Agriculture, Agriculture Research Service, Cereal Disease Laboratory, St. Paul, MN, USA.
Jesse PolandWheat Genetics Resource Center, Department of Plant Pathology, Kansas State University, Manhattan, KS, USA.ORCID http://orcid.org/0000-0002-7856-1399
Harbans BarianaThe University of Sydney Plant Breeding Institute, Cobbitty, New South Wales, Australia.
Jonathan D G JonesThe Sainsbury Laboratory, Norwich Research Park, Norwich, UK.
Alison R BentleyThe John Bingham Laboratory, NIAB, Cambridge, UK.
Mick AyliffeCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, Australian Capital Territory, Australia.
Eric OlsonMichigan State University, East Lansing, MI, USA.
Steven S XuUS Department of Agriculture, Agriculture Research Service, Northern Crop Science Laboratory, Cereal Crops Research Unit, Red River Valley Agricultural Research Center, Fargo, ND, USA.
Brian J SteffensonDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, USA.ORCID http://orcid.org/0000-0001-7961-5363
Evans LagudahCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, Australian Capital Territory, Australia.ORCID http://orcid.org/0000-0002-6234-1789
Brande B H WulffJohn Innes Centre, Norwich Research Park, Norwich, UK. brande.wulff@jic.ac.uk.ORCID http://orcid.org/0000-0003-4044-4346
Funding
Biotechnology and Biological Sciences Research Council BB/E006868/1Biotechnology and Biological Sciences Research Council BB/H019820/1Biotechnology and Biological Sciences Research Council BB/L009293/1Biotechnology and Biological Sciences Research Council BB/P021646/1
Abstract
Disease resistance (R) genes from wild relatives could be used to engineer broad-spectrum resistance in domesticated crops. We combined association genetics with R gene enrichment sequencing (AgRenSeq) to exploit pan-genome variation in wild diploid wheat and rapidly clone four stem rust resistance genes. AgRenSeq enables R gene cloning in any crop that has a diverse germplasm panel.
Indexed as
Cloning, MolecularGenes, PlantChromosome MappingCrops, AgriculturalDisease ResistanceGenetic Association StudiesGenetic VariationGenomicsGenotypeModels, GeneticPhenotypePhylogenyPlant DiseasesPolymorphism, Single NucleotideSeedlingsTriticum
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.