Evidence map›Paper›PMID 30718760›Full record

ArticleScientific reports2019

Patterns of cardiovascular variability after long-term sino-aortic denervation in unanesthetized adult rats.

Alberto Radaelli, Giuseppe Mancia, Caterina De Carlini, Francesco Soriano, Paolo Castiglioni

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alberto RadaelliCardiac Rehabilitation, S. Gerardo Hospital, Monza, Italy. albertorada13@gmail.com.
Giuseppe ManciaUniversità Milano Bicocca, Monza, Italy.
Caterina De CarliniUniversità Milano Bicocca, Monza, Italy.
Francesco SorianoUniversità Milano Bicocca, Monza, Italy.
Paolo CastiglioniIRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.ORCID 0000-0002-8775-2605
University of Milano-Bicocca · ITAzienda Ospedaliera San Gerardo · ITDon Carlo Gnocchi Foundation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baroreflex dysfunction is a diffuse chronic condition that is expected to be followed by a profound loss of organization of BP and HR variability. Nevertheless, long-term effects of baroreflex withdrawal are still debated. Aim of our work was to study BP and HR changes long term after sino-aortic denervation (SAD). Inter-beat-interval (IBI) and intra-arterial BP were recorded beat-by-beat in 43 Wistar-Kyoto rats (Controls, n = 33; SAD rats, n = 10). Power spectra were calculated in controls and in SAD rats within three days and at seven months from denervation. Compared to controls, chronic SAD rats showed 1) similar mean BP (control vs SAD: 95 ± 16 vs 87 ± 22 mmHg) and IBI (171 ± 22 vs 181 ± 15 ms) values, 2) dramatically higher values of BP variance (12 ± 2 vs 64 ± 2 mmHg

Indexed as

AnimalsAortaBaroreflexBlood PressureHeart RateModels, AnimalRatsRats, Inbred WKYSinoatrial NodeSympathectomyTime Factors

Identifiers

PMID30718760
PMCPMC6362124
OpenAlexW2914530555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.