ArticleScientific reports2019
Cognitive ability and risk of death from lower respiratory tract infection: findings from UK Biobank.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Severe infections, domain-specific cognitive vulnerability, and future infection risk in older adults.Brain, behavior, & immunity - health · 2026Article
- Impact of COVID-19 on functional, cognitive, neuropsychiatric, and health-related outcomes in patients with dementia: A systematic review.eNeurologicalSci · 2025Review
- Risk factors associated with functional decline in older hospital survivors with acute lower respiratory tract infections: a prospective cohort study.BMC geriatrics · 2024Article
- Sarcopenia of the longitudinal tongue muscles in rats.Respiratory physiology & neurobiology · 2024Article
- Pre-pandemic cognitive function and COVID-19 vaccine hesitancy: cohort study.Brain, behavior, and immunity · 2021Article
- Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study based on a community sample.Brain, behavior, and immunity · 2020Article
- Ethnic disparities in hospitalisation for COVID-19 in England: The role of socioeconomic factors, mental health, and inflammatory and pro-inflammatory factors in a community-based cohort study.Brain, behavior, and immunity · 2020Article
- Ethnic Disparities in Hospitalization for COVID-19: a Community-Based Cohort Study in the UK.medRxiv : the preprint server for health sciences · 2020Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Dementia increases the risk of lower respiratory tract infection, but it is unclear whether risk varies across the normal range of cognitive ability. People with higher cognitive ability tend to behave in a healthier fashion as regards risk factors for lower respiratory tract infection and there is evidence that they have a lower risk of dying from respiratory disease as a whole. We therefore investigated the relationship between cognitive ability and mortality from lower respiratory tract infection. Participants were 434,413 people from UK Biobank (54% female). Cognitive ability was measured using tests of reaction time and reasoning. Data on deaths from lower respiratory infection were obtained from death certificates. Over a mean follow-up period of 6.99 years, 1,282 people died of lower respiratory infection. Mortality from lower respiratory tract infection fell as cognitive ability increased. For a standard deviation faster reaction time, the age- and sex-adjusted hazard ratio (95% confidence interval) was 0.80 (0.76, 0.83) and the multivariable-adjusted hazard ratio was 0.87 (0.83, 0.91). There were similar though weaker associations when cognitive ability was assessed using a reasoning test. These findings suggest that variation across the normal range of cognitive ability increase risk of dying from lower respiratory tract infection.
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Registered trials
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