Evidence map›Paper›PMID 30718584›Full record

ArticleScientific reports2019

Electrospun patterned porous scaffolds for the support of ovarian follicles growth: a feasibility study.

Liliana Liverani, Nathalie Raffel, Amir Fattahi, Alexander Preis, Inge Hoffmann, Aldo R Boccaccini, Matthias W Beckmann, Ralf Dittrich

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 70 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. In Vitro Development of Primordial Follicles from Human Ovarian Tissue.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Tailor-made 3DFrontiers in endocrinology · 2025
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Liliana LiveraniInstitute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058, Erlangen, Germany. liliana.liverani@fau.de.ORCID 0000-0002-4270-4861
Nathalie RaffelDepartment of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander-Universität Erlangen-Nürnberg, Comprehensive Cancer Center ER-EMN, 91054, Erlangen, Germany.
Amir FattahiDepartment of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander-Universität Erlangen-Nürnberg, Comprehensive Cancer Center ER-EMN, 91054, Erlangen, Germany.
Alexander PreisInstitute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.ORCID 0000-0003-3469-5982
Inge HoffmannDepartment of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander-Universität Erlangen-Nürnberg, Comprehensive Cancer Center ER-EMN, 91054, Erlangen, Germany.
Aldo R BoccacciniInstitute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.ORCID 0000-0002-7377-2955
Matthias W BeckmannDepartment of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander-Universität Erlangen-Nürnberg, Comprehensive Cancer Center ER-EMN, 91054, Erlangen, Germany.
Ralf DittrichDepartment of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander-Universität Erlangen-Nürnberg, Comprehensive Cancer Center ER-EMN, 91054, Erlangen, Germany. ralf.dittrich@uk-erlangen.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the interest of the scientific community is focused on the application of tissue engineering approach for the fertility restoration. In this paper innovative patterned electrospun fibrous scaffolds were fabricated and used as 3D system for porcine follicles culture. The obtained scaffolds demonstrated to be a suitable support which did not alter or interfere with the typical spherical follicles morphology. The fibrillar structure of the scaffolds mimics the morphology of the healthy native tissue. The use of porcine follicles implied many advantages respect to the use of mouse model. Relevant results showed that more than the scaffold pattern and struts dimension, the selection of proper biomaterials improve the follicles adhesion and development.

Indexed as

AnimalsBiocompatible MaterialsFeasibility StudiesFemaleNanofibersOvarian FolliclePorositySwineTissue EngineeringTissue ScaffoldsBiocompatible Materials

Identifiers

PMID30718584
PMCPMC6362199
OpenAlexW2911934486

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.