Evidence map›Paper›PMID 30718479›Full record

ArticleNature communications2019

Single-molecule sequencing detection of N6-methyladenine in microbial reference materials.

Alexa B R McIntyre, Noah Alexander, Kirill Grigorev, Daniela Bezdan, Heike Sichtig, Charles Y Chiu, Christopher E Mason

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed.

  1. Decoding chromosome organization using proximity labeling and long-read sequencing.Journal of genetics and genomics = Yi chuan xue bao · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A pentose, as a cytosine nucleobase modification inApplied and environmental microbiology · 2026
    Article
  7. Article
  8. Nanopore-mFrontiers in genetics · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexa B R McIntyreDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, 10065, NY, USA.
Noah AlexanderDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, 10065, NY, USA.
Kirill GrigorevDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, 10065, NY, USA.
Daniela BezdanDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, 10065, NY, USA.
Heike SichtigUS Food and Drug Administration, Silver Spring, 20993, MD, USA.
Charles Y ChiuDepartment of Laboratory Medicine, University of California San Francisco, San Francisco, 94107, CA, USA.ORCID http://orcid.org/0000-0003-2915-2094
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, 10065, NY, USA. chm2042@med.cornell.edu.ORCID http://orcid.org/0000-0002-1850-1642

Funding

Epigenome Interactions in Complex Neurogenetic DisordersR01NS076465 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASON, CHRISTOPHER EDWARD, ROSS, MARGARET ELIZABETH · 2011 to 2015
$5.8M
Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycleR01AI125416 · NIAID · DUKE UNIVERSITY · PI Stacy Michelle Horner · 2016 to 2026
$5.5M
The Spatiotemporal Landscape of the Human Brain EpitranscriptomeR01MH117406 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASON, CHRISTOPHER EDWARD · 2018 to 2022
$3.3M
Study of Neural Tube Defects Etiology: Genome and ExposomeR01ES021006 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI FINNELL, RICHARD H., MASON, CHRISTOPHER EDWARD · 2012 to 2014
$1.0M
Community Research Education and Engagement for Data Science (CREEDS)R25EB020393 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLAUDIO, LUZ, KOVATCH, PATRICIA · 2015 to 2017
$578k
Mapping the RNA modification N6-methyladenosine during Zika virus infectionR21AI129851 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI HORNER, STACY MICHELLE, MASON, CHRISTOPHER EDWARD · 2017 to 2018
$469k
NIAID NIH HHS R01 AI125416NIAID NIH HHS R21 AI129851NIBIB NIH HHS R25 EB020393NIEHS NIH HHS R01 ES021006NIH HHS 1R21AI129851NIH HHS R01AI125416NIH HHS R01ES021006NIH HHS R01NS076465NIH HHS R25EB020393NIMH NIH HHS R01 MH117406NINDS NIH HHS R01 NS076465
6 · The paper itself

Abstract

The DNA base modification N6-methyladenine (m

Indexed as

AdenosineAlgorithmsDNA MethylationImmunoprecipitationSequence Analysis, DNASoftwareAdenosineN-methyladenosine

Identifiers

PMID30718479
PMCPMC6362088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.