Evidence map›Paper›PMID 30718282›Full record

ArticleThe Journal of biological chemistry2019

The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion.

Mandy M F Steinbusch, Marjolein M J Caron, Don A M Surtel, Guus G H van den Akker, Paul J van Dijk, Franziska Friedrich, Bernhard Zabel, Lodewijk W van Rhijn, Mandy J Peffers, Tim J M Welting

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Viperin is anti-viralThe Journal of general virology · 2021
    Article
  9. Article
  10. Review
  11. Review
  12. Viperin Reveals Its True Function.Annual review of virology · 2020
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Mandy M F SteinbuschFrom the Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery and.
Marjolein M J CaronFrom the Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery and.
Don A M SurtelFrom the Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery and.
Guus G H van den AkkerFrom the Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery and.
Paul J van Dijkthe Department of Anatomy and Embryology, Maastricht University, NL-6202 AZ Maastricht, The Netherlands.
Franziska Friedrichthe University Heart Centre Freiburg, Faculty of Medicine, University of Freiburg, Institute for Experimental Cardiovascular Medicine, 79110 Freiburg, Germany.
Bernhard Zabelthe Medical Faculty, Otto van Guericke University of Magdeburg, 39106 Magdeburg, Germany, and.
Lodewijk W van RhijnFrom the Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery and.
Mandy J Peffersthe Department of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool L69 3BX, United Kingdom.
Tim J M WeltingFrom the Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery and t.welting@maastrichtuniversity.nl.
Maastricht University · NLOtto-von-Guericke University Magdeburg · DEUniversity of Freiburg · DEUniversity of Liverpool · GB

Funding

Medical Research Council MR/P020941/1Wellcome Trust 107471
6 · The paper itself

Abstract

Viperin (also known as radical SAM domain-containing 2 (RSAD2)) is an interferon-inducible and evolutionary conserved protein that participates in the cell's innate immune response against a number of viruses.

Indexed as

ChondrogenesisAnimalsCell LineChemokine CXCL10Gene Knockdown TechniquesHumansMesenchymal Stem CellsMiceOxidoreductases Acting on CH-CH Group DonorsProteinsSignal TransductionSmad ProteinsTransforming Growth Factor betaViperin ProteinChemokine CXCL10Oxidoreductases Acting on CH-CH Group DonorsProteinsRSAD2 protein, humanRsad2 protein, mouseSmad ProteinsTransforming Growth Factor betaViperin Proteincartilage biologycartilage-hair hypoplasiachemokinechondrogenesischondrogenic differentiationC-X-C motif chemokine ligand 10RMRP snoRNAsecretionsmall nucleolar RNA (snoRNA)transforming growth factor beta (TGF-B)viperin

Identifiers

PMID30718282
PMCPMC6442052
OpenAlexW2913266901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.