ArticleAntimicrobial agents and chemotherapy2019
Whole-Genome Sequencing for Drug Resistance Profile Prediction in
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Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 87 citations in OpenAlex.
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- Interpreting antimicrobial resistance from bacterial whole-genome sequencing: prediction tools, database fragmentation, analytical trade-offs, and harmonized reporting.Frontiers in microbiology · 2026Review
- Drug-resistant tuberculosis and pulmonary co-infections in immunocompromised patients: from multi-omics to precision therapy.Frontiers in microbiology · 2026Review
- Nationwide whole-genome sequencing reveals local transmission of Mycobacterium tuberculosis in Poland, 2003-2020.BMC infectious diseases · 2025Article
- Evolutionary trajectories determine feasibility of collateral sensitivity-based antibiotic treatment strategies in critical bacterial pathogens.Communications biology · 2025Article
- Surveillance and analysis of drug resistance and drug resistance levels in multidrug resistant tuberculosis on the tropical islands of China.BMC infectious diseases · 2025Article
- The implications of mutations in multiple genes associated with ethambutol resistance among multidrug-resistant tuberculosis isolates from China.BMC microbiology · 2025Article
- Effects of mutations in multiple Ethionamide-resistance-associated genes amongFrontiers in cellular and infection microbiology · 2025Article
- Mutations inAntibiotics (Basel, Switzerland) · 2024Article
- Co-resistance to isoniazid and second-line anti-tuberculosis drugs in isoniazid-resistant tuberculosis at a tertiary care hospital in Thailand.Microbiology spectrum · 2024Article
- Insights into the novel Enterococcus faecalis phage: A comprehensive genome analysis.PloS one · 2024Article
- Discordance Between Phenotypic and WGS-Based Drug Susceptibility Testing Results for Some Anti-Tuberculosis Drugs: A Snapshot Study of PairedInfection and drug resistance · 2024Article
- Evaluating the Sensitivity of Different Molecular Techniques for DetectingPolish journal of microbiology · 2023Article
- Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance.Journal of clinical tuberculosis and other mycobacterial diseases · 2023Article
- Genetic Characterization ofFoods (Basel, Switzerland) · 2023Article
- Comparative genomics of drug-resistant strains of Mycobacterium tuberculosis in Ecuador.BMC genomics · 2022Article
- Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing ofThe European respiratory journal · 2022Article
- Multidrug-resistant tuberculosis in Finland: treatment outcome and the role of whole-genome sequencing.ERJ open research · 2022Article
Corrections and comments
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Authors and funding
17 authors at 9 institutions in 6 countries.
Sebastian M Gygli *Swiss Tropical and Public Health Institute, Basel, Switzerland.
Peter M Keller *Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland.
Marie BallifInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Nicolas BlöchligerInstitute of Medical Microbiology, University of Zürich, Zürich, Switzerland.
Rico HömkeInstitute of Medical Microbiology, University of Zürich, Zürich, Switzerland.
Miriam ReinhardSwiss Tropical and Public Health Institute, Basel, Switzerland.
Chloé LoiseauSwiss Tropical and Public Health Institute, Basel, Switzerland.
Claudia RitterInstitute of Medical Microbiology, University of Zürich, Zürich, Switzerland.
Peter SanderInstitute of Medical Microbiology, University of Zürich, Zürich, Switzerland.
Sonia BorrellSwiss Tropical and Public Health Institute, Basel, Switzerland.
Jimena Collantes LooInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Anchalee AvihingsanonHIV-NAT/Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Joachim GnokoroCentre de Prise en Charge de Recherche et de Formation, Yopougon, Abidjan, Côte d'Ivoire.
Marcel YotebiengCollege of Public Health, Ohio State University, Columbus, Ohio, USA.
Matthias Egger *Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Sebastien Gagneux *Swiss Tropical and Public Health Institute, Basel, Switzerland sebastien.gagneux@swisstph.ch boettger@imm.uzh.ch.
Erik C Böttger *Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland sebastien.gagneux@swisstph.ch boettger@imm.uzh.ch.
University of Zurich · CHSwiss Tropical and Public Health Institute · CHUniversity of Bern · CHCentre Hospitalier Universitaire de Yopougon · CIHIV Netherlands Australia Thailand Research Collaboration · THThe Ohio State University · USUniversidad Peruana Cayetano Heredia · PEUniversity of Basel · CHWellcome Centre for Infectious Diseases Research in Africa · ZA
Funding
Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9MThe Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8MCCASAnet: Caribbean, Central and South America NetworkU01AI069923 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Pedro Enrique Cahn, Jessica L Castilho · 2006 to 2026
$41.6M"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8MWADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9MNIAID NIH HHS U01 AI069907NIAID NIH HHS U01 AI069919NIAID NIH HHS U01 AI069923NIAID NIH HHS U01 AI069924NIAID NIH HHS U01 AI096299
Abstract
Whole-genome sequencing allows rapid detection of drug-resistant
Indexed as
Antitubercular AgentsDemocratic Republic of the CongoDrug Resistance, Multiple, BacterialEthambutolGenome, BacterialGenotypeHumansMicrobial Sensitivity TestsMutationMycobacterium tuberculosisPeruPhenotypeSwitzerlandThailandTuberculosis, Multidrug-ResistantWhole Genome SequencingAntitubercular AgentsEthambutoldrug resistancedrug resistance level predictionMycobacterium tuberculosisquantitative phenotypic drug susceptibility testingwhole-genome sequencing
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What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.