Evidence map›Paper›PMID 30718255›Full record

ArticleAntimicrobial agents and chemotherapy2019

Evelyne Lacasse, Eric Brouillette, Audrey Larose, Thomas R Parr, Aileen Rubio, François Malouin

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Trial
  3. In vitro and in vivo antibacterial activity of oral tebipenem in combination with novel β-lactamase inhibitors (avibactam, relebactam, vaborbactam) against KPC-producing Enterobacterales.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  4. Review
  5. The oral penems and carbapenems.Clinical microbiology reviews · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Absorption, Metabolism, and Excretion of [Antimicrobial agents and chemotherapy · 2023
    Article
  10. Article
  11. Article
  12. The Class A β-Lactamase Produced byAntibiotics (Basel, Switzerland) · 2022
    Article
  13. Antimicrobial agents and chemotherapy · 2021
    Article
  14. Article
  15. Antimicrobial agents and chemotherapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Evelyne LacasseCentre d'Étude et de Valorisation de la Diversité Microbienne (CEVDM), Département de biologie, Faculté des sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Eric BrouilletteCentre d'Étude et de Valorisation de la Diversité Microbienne (CEVDM), Département de biologie, Faculté des sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Audrey LaroseCentre d'Étude et de Valorisation de la Diversité Microbienne (CEVDM), Département de biologie, Faculté des sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Thomas R ParrSpero Therapeutics, Inc., Cambridge, Massachusetts, USA.
Aileen RubioSpero Therapeutics, Inc., Cambridge, Massachusetts, USA.
François MalouinCentre d'Étude et de Valorisation de la Diversité Microbienne (CEVDM), Département de biologie, Faculté des sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada francois.malouin@usherbrooke.ca.ORCID 0000-0001-5031-345X
Université de Sherbrooke · CASpero Therapeutics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tebipenem (SPR859) is the microbiologically active form of SPR994 (tebipenem-pivoxil), an orally available carbapenem with activity against extended-spectrum β-lactamase (ESBL)-producing

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsPenicillin-Binding ProteinsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsPenicillin-Binding ProteinstebipenemcarbapenemsPBPpenicillin-binding proteinstebipenem

Identifiers

PMID30718255
PMCPMC6437484
OpenAlexW2911869999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.