Evidence map›Paper›PMID 30717795›Full record

ArticleBMC veterinary research2019

Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP

Alicia Otero, Camilo Duque Velásquez, Chad Johnson, Allen Herbst, Rosa Bolea, Juan José Badiola, Judd Aiken, Debbie McKenzie

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Prion shedding is reduced by chronic wasting disease vaccination.bioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Chronic Wasting Disease: State of the Science.Pathogens (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alicia OteroCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, IA2, IIS, Universidad de Zaragoza, Zaragoza, Spain.
Camilo Duque VelásquezDepartment of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
Chad JohnsonDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, USA.
Allen HerbstDepartment of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, Alberta, Canada.
Rosa BoleaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, IA2, IIS, Universidad de Zaragoza, Zaragoza, Spain.
Juan José BadiolaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, IA2, IIS, Universidad de Zaragoza, Zaragoza, Spain.
Judd AikenDepartment of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, Alberta, Canada.
Debbie McKenzieDepartment of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada. debbie.mckenzie@ualberta.ca.ORCID http://orcid.org/0000-0002-9291-6977
University of Alberta · CAUniversidad de Zaragoza · ESUniversity of Wisconsin–Madison · US

Funding

Alberta Prion Research Institute PEX13004Department of Defense National Prion Research Program DAMD17-03-1-0294Genome Canada GC-LSARP
6 · The paper itself

Abstract

backgroundChronic wasting disease (CWD) is a prion disease affecting members of the Cervidae family. PrP

resultsAlthough we detected differences in certain brain areas, globally, the different genotypes showed similar PrP

conclusionsOur data suggest that expression of H95-PrP

Indexed as

DeerAnimalsBrainCerebellumDisease SusceptibilityFrontal LobeGenotypeIntestinesKidneyLymphoid TissueMuscle, SkeletalPancreasPolymorphism, GeneticPrion DiseasesPrion ProteinsSalivary GlandsPrion ProteinsChronic wasting diseaseCWDDeerPeripheral tissuesPolymorphismsPrion diseasesPrionsPrPCWD

Identifiers

PMID30717795
PMCPMC6360794
OpenAlexW2941282533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.