Evidence map›Paper›PMID 30717741›Full record

Observational studyBMC public health2019

Does the economic recession influence the incidence of pertussis in a cosmopolitan European city?

Sílvia Brugueras, Cristina Rius, Joan-Pau Millet, Martí Casals, Joan A Caylà, Barcelona Pertussis Working Group

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06286007 (Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06286007 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control

Typeobservational_patient_registrySponsorHospital Clinico Universitario de SantiagoRan2023 to 2026Enrolled784ConditionsAsthma, Pertussis, RSV InfectionArmsPCR
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Alarm Thresholds for Pertussis Outbreaks in Iran: National Data Analysis.Osong public health and research perspectives · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sílvia BruguerasServei d'epidemiologia, Agència de Salut Pública de Barcelona, Barcelona, Spain. silviabruguerastorrella@gmail.com.ORCID http://orcid.org/0000-0001-6439-0050
Cristina RiusServei d'epidemiologia, Agència de Salut Pública de Barcelona, Barcelona, Spain.
Joan-Pau MilletServei d'epidemiologia, Agència de Salut Pública de Barcelona, Barcelona, Spain.
Martí CasalsSport and Physical Activity Studies Centre (CEEAF), University of Vic-Central University of Catalonia (UVic-UCC), Barcelona, Spain.
Joan A CaylàServei d'epidemiologia, Agència de Salut Pública de Barcelona, Barcelona, Spain.
Barcelona Pertussis Working Group
Universitat Autònoma de Barcelona · ESUniversitat de Vic - Universitat Central de Catalunya · ESAgència de Salut Pública de Catalunya · ESFoundation for Biomedical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the last few years, pertussis has re-emerged worldwide. The aim of this article is to study how the incidence of the disease has evolved in Barcelona city over a 16-year period, and determine which factors are associated with the evolution of the disease. We discuss the causes of the observed changes considering different possibilities such as vaccination coverage, vaccine effectiveness, increased surveillance or the effect of the current economic recession.

methodsWe performed a cross-sectional, observational, population-based descriptive study using data for the 2000-2015 period from the notifiable diseases register maintained by Barcelona Public Health Agency. We used Poisson regression to compute adjusted odds ratios (aOR) and their corresponding 95% confidence intervals (CI).

resultsA total of 1791 cases were registered. The incidence of the disease increased throughout the city from 2011 onwards. While children under 1 year of age had the highest-incidence and were the most at risk (aOR = 27.18, CI:23.51-31.44), we found that the age of affected children was higher in the last years. Incidence proportion (PRR) was lower among foreign-born children than native children (PRR = 0.43 CI:0.32-0.58). In the whole-cell vaccine period (2000-2004), the percentage of cases under 1 year of age who received the vaccine was lower than in 2005-2015 when the acellular vaccine was used (p = 0.01), suggesting a lower efficacy of the acellular vaccine. However, vaccination coverage in children under 6 years remained high (~ 90%), and there were no significant year-to-year variations (p = 0.757). Moreover, there did not appear to be any significant restrictions in medical care. According to the index of disposable household income (DHI), pertussis incidence increased from 2011 onwards in all neighbourhoods and remained higher in those with lower DHI.

conclusionsThe noteworthy increase in pertussis incidence does not seem to be due to the economic recession, but to other factors here described.

Indexed as

Economic RecessionPopulation SurveillanceAdolescentAdultChildChild, PreschoolCitiesCross-Sectional StudiesFemaleHumansIncidenceInfantMalePertussis VaccinePregnancyRegistriesPertussis VaccineBordetella pertussisCitiesEconomic recessionEpidemiologyPertussis vaccineWhooping cough

Identifiers

PMID30717741
PMCPMC6360796
OpenAlexW2922048479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.