Evidence map›Paper›PMID 30717699›Full record

ArticleBMC nephrology2019

Impact of acute kidney injury in expanded criteria deceased donors on post-transplant clinical outcomes: multicenter cohort study.

Woo Yeong Park, Min-Seok Choi, Young Soo Kim, Bum Soon Choi, Cheol Whee Park, Chul Woo Yang, Yong-Soo Kim, Kyubok Jin, Seungyeup Han, Byung Ha Chung

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Optimizing the Use of Deceased Donor Kidneys at Risk of Discard: A Clinical Practice Guideline.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Guideline
  2. Article
  3. Review
  4. Article
  5. Deceased Donor Characteristics and Kidney Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Woo Yeong ParkDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea.
Min-Seok ChoiTransplant Research Center, Seoul, South Korea.
Young Soo KimDivision of Nephrology, Department of Internal Medicine, Uijeongbu St. Mary's hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, South Korea.
Bum Soon ChoiTransplant Research Center, Seoul, South Korea.
Cheol Whee ParkTransplant Research Center, Seoul, South Korea.
Chul Woo YangTransplant Research Center, Seoul, South Korea.
Yong-Soo KimTransplant Research Center, Seoul, South Korea.
Kyubok JinDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea.
Seungyeup HanDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea.
Byung Ha ChungTransplant Research Center, Seoul, South Korea. chungbh@catholic.ac.kr.ORCID 0000-0003-0048-5717
Seoul Medical Center · KRKeimyung University · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe problem of organ shortage is an important issue in kidney transplantation, but the effect of kidney donation on AKI is unclear. The aim of this study was to investigate the impact of acute kidney injury (AKI) on post-transplant clinical outcomes for deceased donor kidney transplantation (DDKT) using standard criteria donors (SCDs) versus expanded criteria donors (ECDs).

methodsFive-hundred nine KT recipients receiving kidneys from 386 deceased donors (DDs) were included from three transplant centers. Recipients were classified into the SCD-KT or ECD-KT group according to corresponding DDs and both groups were divided into the AKI-KT or non-AKI-KT subgroups according to AKI in donor. We compared the clinical outcomes among those four groups and investigated the interaction between AKI in donors and ECD on allograft outcome.

resultsThe incidence of delayed allograft function was higher when the donors had AKI within SCD-KT and ECD-KT groups. In allograft biopsies within 3 months, chronic change was more significant in the AKI-ECD-KT subgroup than in the non-AKI-ECD-KT subgroup, but it did not differ between AKI-SCD-KT and non-AKI-SCD-KT group. AKI-ECD-KT showed higher risk for death-censored allograft failure than the other three groups and a significant interaction was observed between AKI in donors and ECD on the allograft outcome.

conclusionsThe presence of AKI in ECDs significantly impacted the long-term allograft outcomes of kidney transplant recipients, but it did not in SCDs.

Indexed as

Kidney TransplantationTissue DonorsTransplant RecipientsAcute Kidney InjuryAdultAgedCadaverDelayed Graft FunctionDonor SelectionFemaleFollow-Up StudiesGraft SurvivalHumansMaleMiddle AgedOdds RatioAcute kidney injuryDeceased donorExpanded criteria donorKidney transplantation

Identifiers

PMID30717699
PMCPMC6360778
OpenAlexW2942677111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.