Evidence map›Paper›PMID 30717660›Full record

ArticleBMC genomics2019

Exploring the genetics of trotting racing ability in horses using a unique Nordic horse model.

Brandon D Velie, Mette Lillie, Kim Jäderkvist Fegraeus, Maria K Rosengren, Marina Solé, Maja Wiklund, Carl-Fredrik Ihler, Eric Strand, Gabriella Lindgren

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Selection in the Finnhorse, a native all-around horse breed.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Brandon D VelieDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden. brandon.velie@sydney.edu.au.ORCID http://orcid.org/0000-0001-9359-6138
Mette LillieDepartment of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden.
Kim Jäderkvist FegraeusDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Maria K RosengrenDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Marina SoléDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Maja WiklundDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Carl-Fredrik IhlerDepartment of Companion Animal Clinical Sciences, Norwegian University of Life Sciences, Oslo, Norway.
Eric StrandDepartment of Companion Animal Clinical Sciences, Norwegian University of Life Sciences, Oslo, Norway.
Gabriella LindgrenDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Swedish University of Agricultural Sciences · SENorwegian University of Life Sciences · NOThe University of Sydney · AUUppsala University · SE

Funding

Svenska Forskningsrådet Formas (SE) 2016-00947
6 · The paper itself

Abstract

backgroundHorses have been strongly selected for speed, strength, and endurance-exercise traits since the onset of domestication. As a result, highly specialized horse breeds have developed with many modern horse breeds often representing closed populations with high phenotypic and genetic uniformity. However, a great deal of variation still exists between breeds, making the horse particularly well suited for genetic studies of athleticism. To identify genomic regions associated with athleticism as it pertains to trotting racing ability in the horse, the current study applies a pooled sequence analysis approach using a unique Nordic horse model.

resultsPooled sequence data from three Nordic horse populations were used for F

conclusionsNot unexpected for genomic investigations of complex traits, the current study identified hundreds of candidate regions contributing to trotting racing ability in the horse. Likely resulting from the cumulative effects of many variants across the genome, racing ability continues to demonstrate its polygenic nature with candidate regions implicating genes influencing both musculature and neurological development.

Indexed as

PhenotypePolymorphism, Single NucleotideRunningAnimalsBreedingEnergy MetabolismFemaleGenomeGenome-Wide Association StudyHorsesIntelligenceMaleModels, AnimalMuscle DevelopmentSequence Analysis, DNAAthleticismConformationGenomicPerformanceRacehorse

Identifiers

PMID30717660
PMCPMC6360714
OpenAlexW2920157387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.