Evidence map›Paper›PMID 30717497›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Biocompatibility and Bioimaging Potential of Fruit-Based Carbon Dots.

Cindy Dias, Nagamalai Vasimalai, Marisa P Sárria, Ivone Pinheiro, Vânia Vilas-Boas, João Peixoto, Begoña Espiña

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 103 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Nanoformulation ofACS omega · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Cindy DiasINL-International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal. cindydias93@gmail.com.ORCID 0000-0002-9671-7844
Nagamalai VasimalaiINL-International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal. vasimalai.gri@gmail.com.ORCID 0000-0001-5937-3387
Marisa P SárriaINL-International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal. marisa.passos@inl.int.ORCID 0000-0002-3374-8213
Ivone PinheiroINL-International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal. ivone.pinheiro@inl.int.
Vânia Vilas-BoasINL-International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal. vfevilasboas@gmail.com.
João PeixotoCEB-Centre of Biological Engineering, University of Minho, 4720-057 Braga, Portugal. jmp@deb.uminho.pt.
Begoña EspiñaINL-International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal. begona.espina@inl.int.
International Iberian Nanotechnology Laboratory · PTUniversidade do Porto · PTUniversity of Minho · PT

Funding

NORTE2020 (PORTUGAL 2020-ERDF) NORTE-01-0145-FEDER-000019
6 · The paper itself

Abstract

Photo-luminescent carbon dots (CD) have become promising nanomaterials and their synthesis from natural products has attracted attention by the possibility of making the most of affordable, sustainable and, readily-available carbon sources. Here, we report on the synthesis, characterization and bioimaging potential of CDs produced from diverse extensively produced fruits: kiwi, avocado and pear. The in vitro cytotoxicity and anticancer potential of those CDs were assessed by comparing human epithelial cells from normal adult kidney and colorectal adenocarcinoma cells. In vivo toxicity was evaluated using zebrafish embryos given their peculiar embryogenesis, with transparent embryos developing ex-utero, allowing a real-time analysis. In vitro and in vivo experiments revealed that the synthesized CD presented toxicity only at concentrations of ≥1.5 mg mL

Indexed as

biocompatibilitybioimagingcarbon dotscytotoxicityzebrafish embryotoxicity

Identifiers

PMID30717497
PMCPMC6409625
OpenAlexW2914410450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.