Evidence map›Paper›PMID 30717448›Full record

ArticleJournal of clinical medicine2019

Association between Negatively Charged Low-Density Lipoprotein L5 and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients.

Chun-Yu Chang, Chu-Huang Chen, Yi-Ming Chen, Tsu-Yi Hsieh, Ju-Pi Li, Ming-Yi Shen, Joung-Liang Lan, Der-Yuan Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Atherogenic circulating lipoproteins in ischemic stroke.Frontiers in cardiovascular medicine · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Chun-Yu ChangDepartment of Medical Education and Research, Taichung Veterans General Hospital, Taichung 407, Taiwan. chung6556@gmail.com.
Chu-Huang ChenLipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan. cchen@texasheart.org.
Yi-Ming ChenDepartment of Medical Education and Research, Taichung Veterans General Hospital, Taichung 407, Taiwan. blacklark@gmail.com.
Tsu-Yi HsiehDepartment of Medical Education and Research, Taichung Veterans General Hospital, Taichung 407, Taiwan. zuyihsieh@gmail.com.
Ju-Pi LiRheumatology and Immunology Center, China Medical University Hospital, Taichung 404, Taiwan. shenmy1124@gmail.com.
Ming-Yi ShenGraduate Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan. d888203@gmail.com.
Joung-Liang LanRheumatology and Immunology Center, China Medical University Hospital, Taichung 404, Taiwan. jounglancmuh@gmail.com.
Der-Yuan ChenRheumatology and Immunology Center, China Medical University Hospital, Taichung 404, Taiwan. dychen1957@gmail.com.
China Medical University · TWKaohsiung Medical University · TWNational Yang Ming Chiao Tung University · TWTaichung Veterans General Hospital · TW

Funding

Taichung Veterans General Hospital TCVGH 1068702C
6 · The paper itself

Abstract

L5, the most negatively charged subfraction of low-density lipoprotein (LDL), is implicated in atherogenesis. We examined the relationship between plasma L5 levels and the occurrence of subclinical atherosclerosis in patients with rheumatoid arthritis (RA). Using anion-exchange purification with fast-protein liquid chromatography, we determined the proportion of plasma L5 of LDL (L5%) in 64 RA patients and 12 healthy controls (HC). Plasma L5% and L5 levels were significantly higher in RA patients (median, 1.4% and 1.92 mg/dL) compared with HC (0.9%,

Indexed as

electronegative LDLL5low-density lipoprotein (LDL)rheumatoid arthritis (RA)subclinical atherosclerosis

Identifiers

PMID30717448
PMCPMC6406888
OpenAlexW2914481593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.