Evidence map›Paper›PMID 30717440›Full record

ArticleNutrients2019

Associations between the Level of Trace Elements and Minerals and Folate in Maternal Serum and Amniotic Fluid and Congenital Abnormalities.

Rafal Kocylowski, Mariusz Grzesiak, Zuzanna Gaj, Wiktor Lorenc, Ewa Bakinowska, Danuta Barałkiewicz, Constantin S von Kaisenberg, Yvonne Lamers, Joanna Suliburska

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Rafal KocylowskiDepartment of Obstetrics, Perinatology and Gynecology, Polish Mother's Memorial Hospital Research Institute, ul. Rzgowska 281/289, 93-338 Lodz, Poland. rkocylow@gmail.com.ORCID 0000-0003-4094-7103
Mariusz GrzesiakDepartment of Obstetrics, Perinatology and Gynecology, Polish Mother's Memorial Hospital Research Institute, ul. Rzgowska 281/289, 93-338 Lodz, Poland. mariusz.grzesiak@iczmp.edu.pl.
Zuzanna GajDepartment of Obstetrics, Perinatology and Gynecology, Polish Mother's Memorial Hospital Research Institute, ul. Rzgowska 281/289, 93-338 Lodz, Poland. zuzanna.gaj@iczmp.edu.pl.
Wiktor LorencDepartment of Trace Element Analysis by Spectroscopy Method, Faculty of Chemistry, Adam Mickiewicz University in Poznan, ul. Umultowska 89b, 61-614 Poznan, Poland. wlorenc@amu.edu.pl.ORCID 0000-0002-3649-6314
Ewa BakinowskaInstitute of Mathematics, Poznan University of Technology, ul. Piotrowo 3A, 60-965 Poznan, Poland. ewa.bakinowska@put.poznan.pl.ORCID 0000-0002-1211-5046
Danuta BarałkiewiczDepartment of Trace Element Analysis by Spectroscopy Method, Faculty of Chemistry, Adam Mickiewicz University in Poznan, ul. Umultowska 89b, 61-614 Poznan, Poland. danutaba@amu.edu.pl.
Constantin S von KaisenbergDepartment of Obstetrics and Gynecology, Hannover Medical School, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany. vonKaisenberg.Constantin@mh-hannover.de.
Yvonne LamersFood, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T 1Z4, Canada. yvonne.lamers@ubc.ca.ORCID 0000-0001-7878-0164
Joanna SuliburskaInstitute of Human Nutrition and Dietetics, Poznan University of Life Sciences, Poznan, Poland, ul. Wojska Polskiego 31, 60-624 Poznan, Poland. joanna.suliburska@up.poznan.pl.ORCID 0000-0002-0937-8427
Polish Mother’s Memorial Hospital Research Institute · PLAdam Mickiewicz University in Poznań · PLInstitute of Mathematics · PLMedizinische Hochschule Hannover · DEUniversity of British Columbia · CAUniversity of Life Sciences in Poznań · PL

Funding

Polish Ministry of Science & Higher Education Grant No. 2016/I/18-GW
6 · The paper itself

Abstract

Congenital birth defects may result in a critical condition affecting the baby, including severe fetal/neonatal handicap and mortality. Several studies have shown that genetic, nutritional, and environmental factors may have an impact on fetal development and neonatal health. The relevance of essential and toxic elements on fetal development has not yet been fully investigated, and the results of recent research indicate that these elements may be crucial in the assessment of the risk of malformations in neonates. We determined the association between essential and toxic elements and the level of folate in maternal serum (MS) and amniotic fluid (AF), along with neonatal abnormalities. A total of 258 pregnant Polish women in the age group of 17⁻42 years participated in this study. AF and MS were collected during vaginal delivery or during cesarean section. An inductively coupled plasma mass spectrometry technique was used to determine the levels of various elements in AF and MS. The results of this exploratory study indicate that the levels of essential and toxic elements are associated with fetal and newborn anatomical abnormalities and growth disorders.

Indexed as

Fetal DevelopmentAdolescentAdultAmniotic FluidCongenital AbnormalitiesFemaleFolic AcidGrowth DisordersHumansInfant, NewbornMineralsPregnancyTrace ElementsYoung AdultFolic AcidMineralsTrace Elementsamniotic fluidcongenital abnormalitiesmineralsserumtrace elements

Identifiers

PMID30717440
PMCPMC6413094
OpenAlexW2911879197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.