Evidence map›Paper›PMID 30717422›Full record

ArticleInternational journal of molecular sciences2019

Bisoprolol, Known to Be a Selective β₁-Receptor Antagonist, Differentially but Directly Suppresses I

Edmund Cheung So, Ning-Ping Foo, Shun Yao Ko, Sheng-Nan Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Evaluation of Small-Molecule Candidates as Modulators of M-Type KInternational journal of molecular sciences · 2025
    Review
  4. Evidence for Dual Activation ofInternational journal of molecular sciences · 2022
    Article
  5. Article
  6. Zingerone Modulates Neuronal Voltage-Gated NaInternational journal of molecular sciences · 2022
    Article
  7. The Effectiveness in Activating M-Type KInternational journal of molecular sciences · 2021
    Article
  8. Article
  9. Article
  10. Characterization of Effectiveness in ConcertedInternational journal of molecular sciences · 2020
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Edmund Cheung SoDepartment of Anesthesia, An Nan Hospital, China Medical University, Tainan 70965, Taiwan. edmundsotw@gmail.com.
Ning-Ping FooDepartment of Anesthesia, An Nan Hospital, China Medical University, Tainan 70965, Taiwan. D23923@mail.tmanh.org.tw.
Shun Yao KoGraduate Institute of Medical Sciences, Chang Jung Christian University, Tainan 71101, Taiwan. syko@mail.cjcu.edu.tw.
Sheng-Nan WuInstitute of Basic Medical Sciences, National Cheng Kung University Medical College, Tainan 70101, Taiwan. snwu@mail.ncku.edu.tw.
China Medical University · TWChang Jung Christian University · TWNational Cheng Kung University · TW

Funding

An Nan Hospital, China Medical University ANHRF-107-13National Cheng Kung University D106-35A13, D107-F2519NCKUH NCKUH-10709001
6 · The paper itself

Abstract

Bisoprolol (BIS) is a selective antagonist of β₁ adrenergic receptors. We examined the effects of BIS on M-type K⁺ currents (I

Indexed as

Action PotentialsAdrenergic beta-1 Receptor AntagonistsAnimalsBisoprololElectrophysiological PhenomenaKCNQ2 Potassium ChannelKCNQ3 Potassium ChannelMicePituitary GlandPyramidal CellsRatsShaw Potassium ChannelsAdrenergic beta-1 Receptor AntagonistsBisoprololKCNQ2 Potassium ChannelKCNQ3 Potassium ChannelShaw Potassium Channelsbisoprololmembrane potentialM-type K+ channel. erg-mediated K+ currentM-type K+ currentpituitary cell

Identifiers

PMID30717422
PMCPMC6386942
OpenAlexW2912740062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.