Evidence map›Paper›PMID 30717397›Full record

ArticleMarine drugs2019

Saccharoquinoline, a Cytotoxic Alkaloidal Meroterpenoid from Marine-Derived Bacterium

Tu Cam Le, Eun Ju Lee, Jihye Lee, Ahreum Hong, Chae-Yoon Yim, Inho Yang, Hyukjae Choi, Jungwook Chin, Sung Jin Cho, Jaeyoung Ko and 3 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Bacterial terpenome.Natural product reports · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Tu Cam LeDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea. lecamtu5789@gmail.com.
Eun Ju LeeNew Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu 41061, Korea. dmswn2588@naver.com.
Jihye LeeDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea. jl3414@gmail.com.
Ahreum HongGraduate School of Industrial Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea. lyzenne@naver.com.
Chae-Yoon YimDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea. yimgenie@gmail.com.ORCID 0000-0002-2745-1624
Inho YangDepartment of Convergence Study on the Ocean Science and Technology, Korea Maritime and Ocean University, Busan 49112, Korea. ihyang@kmou.ac.kr.ORCID 0000-0003-0990-1465
Hyukjae ChoiCollege of Pharmacy, Yeungnam University, Gyeongsan, Gyeongsangbukdo 38541, Korea. h5choi@yu.ac.kr.ORCID 0000-0002-7707-4767
Jungwook ChinNew Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu 41061, Korea. jwchin@dgmif.re.kr.ORCID 0000-0001-6060-0508
Sung Jin ChoNew Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu 41061, Korea. sjcho@dgmif.re.kr.ORCID 0000-0002-4786-8830
Jaeyoung KoBasic Research & Innovation Division Amorepacific R&D Unit, Yongin 17074, Korea. jaeyoungko@amorepacific.com.
Hayoung HwangNew Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu 41061, Korea. hwanghy@dgmif.re.kr.
Sang-Jip NamDepartment of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea. sjnam@ewha.ac.kr.
William FenicalCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California-San Diego, La Jolla, CA 92093-0204, USA. wfenical@ucsd.edu.
Ewha Womans University · KRDaegu-Gyeongbuk Medical Innovation Foundation · KRAmorepacific (South Korea) · KRKorea Maritime and Ocean University · KRScripps Institution of Oceanography · USYeungnam University · KR

Funding

National Institutes of Health R37 CA044848National Research Foundation of Korea 2017R1D1A1B03028172
6 · The paper itself

Abstract

A cytotoxic alkaloidal meroterpenoid, saccharoquinoline (

Indexed as

ActinobacteriaAntineoplastic AgentsCell Line, TumorCell SurvivalHumansModels, MolecularMolecular StructureTerpenesAntineoplastic AgentsTerpenescytotoxicitymarine natural productmeroterpenoidSaccharomonospora sp.

Identifiers

PMID30717397
PMCPMC6410326
OpenAlexW2913266182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.