Evidence map›Paper›PMID 30717291›Full record

ArticleJournal of clinical medicine2019

A Novel Osteotomy Preparation Technique to Preserve Implant Site Viability and Enhance Osteogenesis.

Chih-Hao Chen, Benjamin R Coyac, Masaki Arioka, Brian Leahy, U Serdar Tulu, Maziar Aghvami, Stefan Holst, Waldemar Hoffmann, Antony Quarry, Oded Bahat and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chih-Hao ChenDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. chchen5027@gmail.com.ORCID 0000-0001-7213-2596
Benjamin R CoyacDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. benjamin_coyac@hotmail.fr.
Masaki AriokaDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. maziara@stanford.edu.
Brian LeahyDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. bleahy94@gmail.com.
U Serdar TuluDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. serdartulu@gmail.com.
Maziar AghvamiDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. maziara@stanford.edu.
Stefan HolstNobel Biocare Services AG P.O. Box, CH-8058 Zürich-Flughafen, Switzerland. stefan.holst@nobelbiocare.com.
Waldemar HoffmannNobel Biocare Services AG P.O. Box, CH-8058 Zürich-Flughafen, Switzerland. waldemar.hoffmann@nobelbiocare.com.ORCID 0000-0002-5652-735X
Antony QuarryNobel Biocare Services AG P.O. Box, CH-8058 Zürich-Flughafen, Switzerland. antony.quarry@nobelbiocare.com.
Oded BahatPrivate Practice, Beverly Hills, CA 90210, USA. odedbahat@gmail.com.
Benjamin SalmonParis Descartes-Sorbonne Paris Cité University, EA2496, Montrouge, France. benjamin.salmon@parisdescartes.fr.ORCID 0000-0001-8739-2753
John B BrunskiDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. brunsj6@stanford.edu.
Jill A HelmsDivision of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA. jhelms@stanford.edu.

Funding

Mechanobiology at Healing Bone-Implant InterfacesR01DE024000 · NIDCR · STANFORD UNIVERSITY · PI BRUNSKI, JOHN BEYER, HELMS, JILL A · 2014 to 2018
$3.4M
NIDCR NIH HHS R01 DE024000NIH HHS R01 DE024000-12Nobel Biocare Services AG, Gothenburg, Sweden 2015-1400
6 · The paper itself

Abstract

The preservation of bone viability at an osteotomy site is a critical variable for subsequent implant osseointegration. Recent biomechanical studies evaluating the consequences of site preparation led us to rethink the design of bone-cutting drills, especially those intended for implant site preparation. We present here a novel drill design that is designed to efficiently cut bone at a very low rotational velocity, obviating the need for irrigation as a coolant. The low-speed cutting produces little heat and, consequently, osteocyte viability is maintained. The lack of irrigation, coupled with the unique design of the cutting flutes, channels into the osteotomy autologous bone chips and osseous coagulum that have inherent osteogenic potential. Collectively, these features result in robust, new bone formation at rates significantly faster than those observed with conventional drilling protocols. These preclinical data have practical implications for the clinical preparation of osteotomies and alveolar bone reconstructive surgeries.

Indexed as

bone chipsbone healingdrilling tool designosteogenesisosteotomy

Identifiers

PMID30717291
PMCPMC6406409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.